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Assessment Of Right Ventricular Diastolic Function In Patients With Essential Hypertension By Doppler Tissue Imaging

Posted on:2004-03-21Degree:MasterType:Thesis
Country:ChinaCandidate:X D YangFull Text:PDF
GTID:2144360092995964Subject:Medical imaging and nuclear medicine
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PrefaceEssential hypertension is one of the mankind's common diseases, not merely incidence rate in population is high, and can cause the serious harm of important organs, such as blood vessel, heart, brain, kidney, etc. For many years, there are a lot of reports about essential hypertension impair function of heart, It is mainly about the left ventricular function, the change of the right ventricular function is relatively less in research, But the right ventricular function has very important in maintaining circulation. So, it is a very essential and meaningful to find a better measurement right ventricular function method. Doppler tissue imaging is a newer ultrasonic inspection method. This technology is to use the low open wave filter to delete the blood flow signal, deal with the return waves echo signal of high amplitude, low speed organized, Show heart message practical thing of sport that comes out in the form of two - dimentional colored picture or the frequency spectrum curve. Use DTI measurement right ventricular function, have the following merits; Neednt draw right ventricular membrane in the heart, because it is very difficult to draw right ventricular membrane accurate; Neednt calculate right room capacity, because of right ventricle's form that without accurate mathematics model come and calculate right ventricular capacity. So it measure result have high credibility and repetitiveness.Material and methodResearch object: normal contrast group of 20 subjects ( males 10,females 10,age 29-68 years, 53.77+5. 69 years). Case group of 60 patients, classify method according to Gannu, and relative wall thickness ( RWT) divide into four groups with left ventricular weight index ( LVMI) , Normal left ventricular construct group( I group): males 9, females 5, age 55. 35+10.44 years; centripetal reconstruct group ( II group) : males 6, females 7, Age 50. 8+11.12 years; concentric hypertrophy group(III group) : males 10, females 8, Age 56. 65+13. 45 years; eccentric hypertrophy group( IVgroup) : males 7, females 8, Age 61. 3+14. 07 years. These patients that diabetes, rheumatic mitral valve, arrhythmia, pulmonary hypertension were exclude.Ultrasonic examination: Both patients and control subjects underwent conventional two-dimensional echocardiography with the instrument of HPSonos with a 2 - 4MHz phased array transducer and DTI software with the patients in the left lateral decubitus position. In each patients, parasternal long axis view were taken to detect the AO, LA, LVDed, IVSth, LVPWth. Then the DTI was activated at apical four -chamber and right ventricular two - chamber view to detect peak velocity and IVRT of TV at early and late term of diastole by pulse Doppler. Making averages of 3 - 5 cardiac cycle as its values, then make averages of tricuspid annulus as average Ea,Aa,IVRT of each group and calculate Ea/Aa at same time. Left ventricular muscle index: LVMI(g/m2) =LVM(left ventricular muscle )/BSA ( body surface area) ,LVM(g) =0. 8 + 1. 04 + [ (IVSth + LVPWth + LVDed)3- LVDed3 ] + 0. 6, relative wall thickness RWT = ( IVSth + LVP-Wth)/LVDed, normal value; LVMI: males < 111g/m2, females < 106g/m2, RWT< 0.44, I group: LVMI and RWT are in the normal range, H group: RWT exceeds normal range, LVMI is in the normal range, IIIgroup: LVMI and RWT exceed the normal range, IVgroup: LVMI exceeds the normal range, RWT is in the normal range.Statistical analysis; all data acquired was analyzed using SPSS 10.0 software. P <0.05 has remarkable meanings for the difference.ResultsThese parameters were contrast of contrast group and essential hypertension group; There are not difference about age and sex of five group subjects, LVM is obviously increases of M , IV group. RWT of III group is the thickest, RWT of IV group is thin. Compared with contrast group, the size of right atrium was changed obviously in IVgroup.average Ea/Aa values of essential hypertension every group is smaller than 1, average Ea values of every group is decreased ( P, < 0. 01) ; Every group IVRT show a...
Keywords/Search Tags:Doppler tissue imaging, Essential hypertension, Tricuspid annular, Right ventricular diastolic function
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