| Objective: The key to treat acute cerebral infarction was to diagnose it qualitatively in the early period, to detect and evaluate ischemic penumbra (IP) and to recover the function of IP as early as possible so that the infarction volume was reduced and prognosis was ameliorated. We tried to study the features of perfusion computered tomography and brain electrical activity mapping (BEAM) in acute cerebral infarction, quantitative analysis and correlation of parameters in order to discuss the applied value of perfusion CT and BEAM in qualitative diagnosis, quantitative assessment of severity, judging the infarction core and IP.Methods: 33 patients during the initial 3～24 hours after the onset of acute cerebral infarction were examined by conventional CT, perfusion CT and BEAM at hospitalization. Patients without abnormality in the first conventional CT examination were re-examinated on the second day to the second month. Conventional CT examination using the OM line as base line scanned upward until the twentieth scan, the scan thickness was 5 mm. Perfusion CT examination wasafter conventional CT, We selected basal gangliar and the upper or lower scan to it, or the scan include the most significant lesion and the upper or lower scan to it as perfusion scans. Contrast medium was injected via antecubital vein by using a power injector. After 6 seconds from injection starting, raw data were acquired by rotating the X-ray tube continuously. Each 360。rotation took 1 second, and the total acquisition time was 40 seconds. The 80 reconstructed images were processed by using private cerebral perfusion software. Perfusion images were analysesed quantitatively though drawing ROI manually in single side or in double sides mirrorly. BEAM examination used electrode cap with the machine. It had 21 electrodes laying according to international 10/20 system. We traced EEG 3 minutes with the earlobes as reference eletrodes, and 30 seconds EEG without confusion was input computer to FTT exchange to obtain power distribution images and we analysesed δ images in this experiment. We studed the features and positive rate of conventional CT, perfusion CT and BEAM in acute cerebral infarction. Parameters of perfusion CT were measured quantitatively in infarction core and IP, the whole lesion and opposite corresponding region and were analysesed statisticly .In accordance with 《Score Standard of Clinical Neurologic Impairment Degree of Stoke Patient》, we dvide the patients into slight group, moderate group and serious group and analyses thedifferences among these groups. We studied the correlation among the parameters of perfusion CT. We measured the mean power of δ in infarction regions and opposite corresponding regions and evaluated their differences. We studied the correlationship of CBF, CBV and mean power of δ. Results: ⑴During 24 hours after cerebral infarction onset, positive rate of conventional CT is 33.3％, positive rate of perfusion CT is 87.9 ％, and BEAM is 90.3％. There were signigicant differences between conventional CT and BEAM, perfusion CT. There were no significant differences between BEAM and perfusion CT. (2) BEAM could define the side of infarctions, but could not localize it accurately. Perfusion CT could define the side and localization of infarction accurately. (3)CBF,CBV,TP were very significant differences(P﹤0.01)and TS,PE were significant differences(P﹤0.05)between infarction core and IP. CBF in infarction core was 6.21±2.71ml/min/100g and in IP was 19.28±4.73 ml/min/100g. CBF was very significant differences(P﹤0.01), CBV,TP were significant differences(P﹤0.05)and TS,PE were no significant differences(P≥0.05)between the whole lesions and opposite corresponding regions. CBF,CBV,TP,TS ,PE were very significant differences among slight group, moderae group and serious group. (4) CBF and CBV were positive correlation, the linear regression equation was y=0.2670+0.1669x and correlationcoefficient was 0.9313. CBF and TP had negative co...
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