| Purpose: To explore the theory basis and the best programme in the clinical prevention and cure of chloasma, we observed the clinical efficacy of treating adult female chloasma with acupuncture and moxibustion and the effect on those treated patients hemorheology by analysing the improvement of cutaneous pigmentation and the change of the whole blood viscocity(ηb) in the condition of high shear rate , middle shear rate, low shear rate, hematocrit(Hct) and erythrocyte electrophoresis time(EET) in hemorheology. The effective mechanism of acupuncture and moxibustion treating adult female chloasma was studied .Methods: According to the clinical diagnostic criterion of the national combined traditional Chinese and western medicine dermatological dyschromatosis committee,40 chosed adult female chloasma patients were randomly divided into 2 groups(n= 20) , treatment group (group A) and medicine control group(group B), Group A was treated by Acumoxi. Group B was given by the medicine Vitamin E and C complex. Sixty days later, between different groups the five hemorheological indexes and the cutaneous pigmentation conditions were estimated. The relation was observed among the clinical efficacy > the skin damage mark the disease course and year.Results: (1) There were no evident difference between the two groups in skin damage mark and the whole blood viscocity(ηb) in the condition of high shear rate , middle shear rate, low shear rate, Hct, EET levels before treatment (P > 0.05), whereas except Hct both of them decreased after treatment (P<0.01) . (2)The levels of the whole blood viscocity(ηb) and EET and skin damage mark in acupuncture and moxibustion group decreased more markedly than those in the medicine control group (P < 0.01) . Hct has no evident difference. (3) There was very obvious difference between the acupuncture andmoxibustion group and the medicine control group (P<0.01) . (4)The whole blood viscocity(ηb) and EET concentration were positively correlated in middle degree with the skin damage mark (P < 0.01) , while Hct has no obvious difference. (5)The skin damage mark were positively correlated in low degree with the disease course (P < 0.05) , negatively correlated in low degree with the mark decreasing index (P < 0.05) ,and the disease course negatively correlated in low degree with the mark decreasing index (P < 0.05) .The others have no obvious difference (P>0.05) .Conclusion: (1) Acupuncture and moxibustion have better clinical efficacy on the adult female chloasma than the medicine Vitamin E and C complex . (2) Chloasma should be treated in the early period,and the shorter the disease course, the better the clinical efficacy . (3) Acupuncture and Moxibustion can improve the hemorheology , which may be an important mechanism to treat chloasma . |
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