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A Comparative Study On Treadmill Exercise Testing And Coronary Angiography For The Diagnosis Of Coronary Heart Disease

Posted on:2005-06-08Degree:MasterType:Thesis
Country:ChinaCandidate:J SunFull Text:PDF
GTID:2144360122498019Subject:Department of Cardiology
Abstract/Summary:PDF Full Text Request
Objective to detect metabolic equivalents (METS), exercise timing and maximum heart rate of the patients. Meanwhile, ST segment fluctuations and whether pectoris angina is accured were monitored by 12 leads electrocardiogram. The patients underwent coronary angiography and left ventriculography at appropriate time to investigate the extent of coronary artery disease and left ventricular ejection fraction(LVEF). The study is to elucidate the diagnositic value and stenosis degree of treadmill exercise testing in coronary artery disease (CAD).Methods ninty-four patients were examined by coronary angiography (CAG) and treadmill exercise testing. To detect metabolic equivalents (METs), exercise timing and maximum heart rate of the patients. Meanwhile, ST segment fluctuations and whether pectoris angina is accured were monitored by 12 leads electrocardiogram. The patients underwent coronary angiography and left ventriculography at appropriate time to investigate the extent of coronary artery disease and left ventricular ejection fraction(LVEF). Analyze the results and process it with SPSS.Results The more heavier coronary artery obstacled,the more earlier will it be when ST segment depression occurred. So as the ST amplitude and the time it lasted. The sensitivity specificity positive predictive value and negative predictive value in predicting multivessel disease by exercise -induced ST segment depression >0.1mV was 76% , 36% , 81%, 71% respectively. The sensitivity specificity positive predictive value and negative predictive value in predicting multivessel disease by METS<6.0 was 44% 85% 92% 70%. However, the sensitivity specificity positive predictive value and negative predictive value in predicting multivessel disease by exercise -induced ST segment depression >0.2mV was 16% 85% 80% 78% respectively .By combining low workload and ST segment depression was 64%93% 97% 58% respectively. METs maximum heart rate and exercise timing were not statistically significant between the single vessel disease and two vessel disease.(p>0.05) . Whereas, the three parameters mentioned above were statistically significant between single vessel disease and three vessel disease as well as two vessel disease and three vessel disease (P<0.05). No significantly comparable relations between the location of coronary artery disease and leads with positive ST segment changes were found out simultaneously. The leads with higher distributing frequencieswere II, III, aVF/V2 V3 V, V5 V6.Conclusions (1) Exercise ECG test is an effective non-invasive method in the diagnosis of CAD . Some parameters in ECG test are helpful to predict the severity of CAD. (2)No significantly comparable relations between the location of coronary artery disease and leads with positive ST segment changes were found out simultaneously.(3) (4)There is an negtive correlation between the degree of coronary artery stenosis and metabolic equivalents (5)Whether there was pectoris angina contributed to determine single-vessel disease or multi-vessel disease.
Keywords/Search Tags:Treadmill exercise testing, coronary angiography, coronary artery disease
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