| IntroductionThe complications of enucleation and evisceration are socket and deformity. Hydroxyapatite (HA) orbital implants have be accepted and used extensively. The clinical effect of our national products coralline hydroxyapatite is well. The benefits and complications are related to vascularization course of the HA implants . To make the HA implants in normal physio - behavior and to decrease complications, it is wrapped with oneself or xenoma materials to implants. To obtain materials easily and decrease complications, the animal experiment of the HA implantation wrapped with the polyester surgical fabrics will provide the science base of clinical application of new materials.Materials and Methods, 12 rabbits were divided 4 groups and they had eye enucleated then received a 12mm HA sphere wrapped in polyester surgical fabrics. The conjunctiva! sac was examined everyday in one week and at 2, 3, 4, 6, 8, 10, 12, 16, 18 weeks postoperatively. One group were killed at 3, 6, 10, 18 weeks respectively after implantation , the implant was removed and cut open for observing and histopathological examinarion.ResultsAll the conjunctival wounds were healing well and no complication. All theHA implants adhere to the orbital tissue. The polyester surgical fabrics were tightly adherence to all the HA spheres and wrapped connective tissue and a few fat. At 3 weeks, to cut open the HA sphere showed the fibro ?vascular tissue ingrowth 2-3 mm from edge to center. At 6 weeks, the fibro - vascular tissueingrowth 4-5 mm. At 10 weeks, the HA sphere were full of fibro - vascular tissue. At 18 weeks, the fibro - vascular tissue in the HA sphere were intensive and firm. After decalcification, the HA sphere left reticularformation and the polyester surgical fabrics keep well and adherence to it tightly. HE stained, the section showed the fibro - vascular tissue invaded the interconnecting pores and the vascularization became intensive after implantation gradually.DiscussionEnucleation and evisceration will following socket and deformity. The mo-tility of the prosthesis will be limited which influence normal cosmetic result. For many years, the scholars have been searching ideal orbital implants. Many kinds of biological and no ?biological materials were not applicable as orbital implants for complication. Ideal orbital implants should have satisfactory motility and normal cosmetic result and few complication. In 1985, Perry had used the HA for the orbital implant first. After experimental research and clinical application , the HA had showed the benefits as an ideal orbital implant. Our national products HA with good clinical effect and are thought to be safe and effective orbital implants. The benefits and complications are related to vascularization course of the HA implants. The more the area of the HA contact to the orbital tissue, the fast of the rate of the the vascularization course of the HA implants. The most complication is the exposure of the implant. The causes of these complications are HAs mechanical and chemical stimulation to the conjunctiva. According to the statistics, the incidence of the implants exposure are 7% and 40% that they are wrapped or unwrapped respectively. To prevent the implants exposure, many people wrap it and then to implant. The wrapping materials are oneself sclera or xenoma materials. Both theirs source are limited. The polyester surgical fabrics have good compatibility and convenience to get and no possibilityof necrosis. The experiment of the HA implantation wrapped with the polyester surgical fabrics for animal, the result confirm that the polyester surgical fabrics have good compatibility to the orbital tissue and do not obstruct the course of vascularization of the HA implants. It is a good substitute for sclera and has no risk.ConclusionThe experiment suggested, the polyester surgical fabrics have good compatibility to the orbital tissue. The vascularization of the HA implants is well and has no complication . It can substitute for wrapping th...
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