| Objective: To investigate the characteristics of distribution and risk factors of asymptomatic intracranial arterial stenosis in patients with diabetes mellitus (DM). Methods: Inpatients (347 cases) with diabetes mellitus examined with transcranial Doppler sonography (TCD) were included. Those with all kinds of stroke, stroke history, or other intracranial diseases were excluded. Intracranial arterial stenosis and the stenosis-grade were evaluated with TCD. The characteristics of distribution and the correlation of asymptomatic intracranial arterial stenosis to age, duration of disease, blood pressure, hyperlipidemia, hyperuriemia and ECG abnormities were analyzed with SPSS 10.0 software.Results: 1. The prevalence of intracranial arterial stenosis was 31.1% (108/347); among 2611 arteries checked, 265 arteries with stenosis were detected, the rate of stenotic artery was 10.15%. The stenosis in internal carotid arterial (ICA) system was more common than that in vertebro-basilar arterial (VBA) system, the most common site of stenosis was in middle cerebral artery (MCA). 2. Age, duration of DM, concomitant hypertension, ECG abnormities, systolic pressure (SP), plasma low density lipoprotein (LDL-C) and uric acid (UA) in patients with arterial stenosis were statistically different from those in patients without stenosis; Logistic regression analysis showed that age, duration and concomitant hypertension were independent risk factors for asymptomatic intracranial arterial stenosis. 3. The grade of intracranial arterial stenosis was correlated to age, duration of DM, SP and plasma UA level.Conclusions: The stenosis in ICA system is more common than in VBA system, the most common involved artery is MCA. Age, duration of DM and concomitant hypertension are independent risk factors for intracranial arterial stenosis in diabetics. Meanwhile, increased SP, high LDL-C level, hyperuriemia and ECG abnormities may as well function as prediction factors for intracranial artery stenosis in diabetics.
|
PDF Full Text Request