| ObjectiveThink now that the HSP70 has many a malignant tumors of the human body very much the good immunization, traditional immunity thing, BCG, is already getting clinical application and already confirming its curative effect, this studying purpose is to evaluate the tumor source HSP70 and BCG uniting application to small rat in cancer of the liver function. For HSP70 of the applied tumor source cure the human malignant tumor the offering consults basis.MethodsUsing the FPLC system separates and purees HSP70 from the small rat tumor cell stub, and proceed the qualitative analysis to each outcome a SDS-PAGE and Western- blots, then authenticate its pure degree. Passing the animal experiment observes HSP70, BCG alone and unites applied anti- tumor function.ResultThe result expresses each treatment set all shows to suppress the tumor function.( P<0.05, or P<0.01).Pass the a compares to discover, HSP70 treatment set is better than the BCG set in a curative effect in treatment. ( P<0.01). Unite the treatment set is better than alone applied two set. ( P<0.05 or P<0.01). Apply the immunity treatment empress, the small rat exists period all contain extension, comparing in the matched control showed the much difference. ( P<0.01). Among them unite the treatment a curative effect is particularly obvious, having 5 small rats get to have a long period of time survives without tumor, three have tumors but survive, survival rate 66.7%. Matched control set 28 days all die, neither survive over a long period of time, mortality 100%.Slice to take the tumor organizes an immunity set turns the manifestation, curing the obvious and lower than matched control in a male rate, expressing the tumor got the immunity represses, among them unite set in each comparison shows the obvious significance difference. HSP70 set is better than the set of BCG in a curative effect.ConclusionThe HSP70 of the tumor source has the clear and definite treatment...
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