The Experimental Study Of Strain Change During Mandibular Distraction Osteogenesis

Distraction osteogensis (DO) are becoming wildly accepted in the field of oral and maxillofacial surgery in recent years. It's based on the principle of strain-stress whose effects on new bone generation during DO is still not known. Although in clinical works, the latency time, distraction rate and frequency, and consolidation time have a common guide, the real effects on bone remolding via the change of strain and stress on distraction area are not well-known. So, in this experiment, we established a rabbit model that could take record of strain during DO. We studied the strain change during latency time, distraction and consolidation time, respectively. To evaluate the effects of distraction osteogenesis, we analyzed the strain trend during distraction from the sight of biomechanics.Part I: This part was to establish an animal model with strain-testing measurement during mandible distraction osteogenesis, including right operative position and encapsulation. After osteotomy of the junction of mandibular body and ramus, setting the customized distracter, and 4days' latency, distraction was managed to lmm/day, twice /day and lmm/day, once/day for 5days, respectively. 2 weeks later, animals were sacrificed for investigation of radiography and histology. The results...