| Pogostemon cablin (Blanco) Benth. is one of famouse traditiongal Chinese medicine in the south of our coutry. The source of Pogostemon cablin (Blanco) Benth. .which is recorded in 《Chinese Pharmacopoeia》 (the version of 2000,1 set), is the dried and upper part of the earth of Pogostemon cablin ( Blanco) Benth. of Lemiaceae. The function of it is removing dampness by means of aromatics, relieving stomach and stopping vomit, relieving superficies syndrome. Applying the following symptom: retention of damp in the middle-energizer, Summer-heat and damp , accidie, Feeling of discomfort and fullness in the chest and hypochondrium, cramp and diarrhea, etc. Except of drug of aromatics for Removing Damp, Pogostemon cablin (Blanco) Benth.According to the different producing area, Pogostemon cablin (Blanco) Benth. can be separated into Pogostemon cablin (Blanco) Benth. cv shipaiensis; Pogostemon cablin (Blanco) Benth. cv gaoyaoensis; Pogostemon cabling Blanco )Benth. cv zhanjiangeensis and Pogostemon cablin (Blanco) Benth. cv hainanensis in the current market. Pogostemon cablin (Blanco) Benth. has a long remedy history . But there are distinct different parlance about its history recordation. Pogostone and patchouli apcohol , both of the volatility components, are considered as the main function composition. The literature mostly reports the oil of Pogostemon cablin (Blanco) Benth.. The Chinese Pharmacopoeia 2000 carry on TLC to distinguish Pogostemon cablin (Blanco) Benth. cv shipaiensis and Pogostemon cablin (Blanco) Benth. cv hainanensis. Contraposing non-volatility components, scholar asunder and identify several compounds,and do some pharmacology experiments in search of effectual part. Which seems not to be suitable for quality control of Pogostemon cablin (Blanco)Benth.In order to establish methods of quality control for this drug, several studies have been conducted e. g. textual research of history recordation of Pogostemon cablin (Blanco) Benth., mensurating Pogost-emon。 cablin (Blanco) Benth. routine index of quality evaluation, mensurating the content of its volatility components by GC, researching on the development of volatility components of Pogostemon cablin (Blanco) Benth. cv shipaiensis which is reproduced by tissues culture by GC-MS, establishing TLC and HPLC chromatographic Fingerprint of Pogostemon cablin (Blanco) Benth..The results showed as the follows:1. Pogostemon cablin (Blanco) Benth. is recorded by 《yi wu zhi》 at first, written by YangFu in han dynasty. As a herb, "huo xiang" appear in 《Records of Famouse Physicians》 initially. But it can be affirmed that it is Pogostemon cablin (Blanco) Benth.. Through literature search , "guang huo xiang" appear in 《traditional Chinese medicine message》 (1957,3(5)) initially.2. Mensuration of routine index of quality evaluation: impurity under 0. 20%, containing water under 14. 0%, total ash under 10. 00%, water-solubility immersesing substance above 5. 0%(cool water) or 9.0% (warm water), ethanol immersesing substance above 2. 0%(cool ethanol) or 4.0% (warm ethanol), the content of heavy metal under 20mg/kg, 666, DDT etc , can not be found in Pogostemon cablin (Blanco) Benth., the content of naphtha must be above 0. 25% (ml/g) .3. By GC, different producing areas have the defference of the total content of Pogostone and patchouli apcohol. Establish the standard that the total content of Pogostone and patchouli apcohol of Pogostemon cablin (Blanco) Benth. cv shipaiensis must be above 55%.4. By GC-MS, researching on the development of volatility components of Pogostemon cablin (Blanco) Benth. cv shipaiensis which is reproduced by mericlone . Because the time of investigation is not enough , it can not be formed an opinion about the best harvest time .5. A HPLC Fingerprint has been established for the identification of f lavonoid of this drug. 11 peaks could be considered as the characteristic...
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