| Primary liver cancer (PLC) with portal vein tumor thrombi (PVTT) was the later .In this case ,the spread and metastatic often occur within the liver.In the past years,the conservative treatment was elected,even given up treatment.But in these years chemotherapy and surgical resection are operated.In the present,the standard and effect have been not concordant in the different treatment.In our study,to compare the therapeutic effect and significance of different treatment methods for primary liver cancer (PLC) with portal vein tumor thrombi (PVTT). In this study, 31 patients with PLC accompanied by portal bein tumor thrombi were treated in our hospital.Patients were divided three groups :A :surgical resection group n=13,B:cheotherapy group n=8 C:resection plus TACE n=10.The median survival period was compared among the 3 groups. The results showed:1)The median survival period was 10.3, 7.1, 13.4months in group A B C respectively.Their0.5 ,1 and 2 year survival rates was 46.2%,15.4% and 0 in group A;37.5%,12.5% and 0 in group B,50%,30% and 20% in group C.There were no significance between the group A and group C.The survival rates differed significancy between the group A and group C , the group B and group C.(P<0.05=.2= The0.5 ,1 and 2 year survival rates was 26.9%,18.2% and 18.2% in group PLC patients with tumorthrombi in first branch of portal vein .;41.7%,29.8% and29.8% in group PLC patients with tumorthrombi in second branch of portal vein;which indicated the surgical treatment can prolong the survival of PLC. The effect of surgical treatment was bad in the main portal vein than in the second branch.3)Statistics analysis reveales that the size of tumor, the position of thrombi and chemotherapy would effect the clinical result. Conclusions: Surgical treatment for PLC is effective. TACE after operation can enhance the effect and prolong the survival time of patients with PLC accompanied by portal vein tumor thrombi. |
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