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Meta Analysis Of Curative Effect Of Traditional Chinese Medicine In Treating Late Patients With Primary Liver Cancer And Traditional Chinese Mediicine Thrombus Syndrome Analysis Of Primary Liver Cancer With Portal Vein Tumor

Posted on:2011-04-06Degree:MasterType:Thesis
Country:ChinaCandidate:X YaoFull Text:PDF
GTID:2154330332467228Subject:Integrative Medicine
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Objective:1. Using Meta analysis software of traditional Chinese medicine for treatment of advanced hepatocellular carcinoma systematic evaluation.2. Retrospective analysis of patients with primary liver cancer with portal vein tumor thrombus of dialectical argumentation, its Chinese dialectical classification and summary of the common drug laws.Methods:1. Using Meta analysis software system for evaluation of Chinese medicine for treatment of advanced primary liver cancer, which traditional Chinese medicine treatment of hepatocellular carcinoma with portal vein tumor thrombus to evaluate the efficacy. Through the years 1999-2008 published in Chinese medicine for treatment of advanced primary liver cancer and the treatment of modern Western medicine as a control group, randomized controlled study of literature search, According to selected, excluding standard-setting selected papers, selected literature on the quality evaluation of literature, the outcome of the literature data taking, using RevMan4.2 (Review Manager) software for statistical analysis, obtained Meta analysis, and conduct bias and sensitivity to analysis.2. Through the Chinese medicine hospital in Zhejiang province during the period 2003-2009, primary liver cancer with portal vein tumor thrombus cases of the collection, According to selected, excluding the standard for ascertaining the successful cases, a retrospective of selected cases of dialectical sub-types of TCM, Chinese medicine treatment (hospitalization for the first time a prescription medicine), and liver function in Child classification was extracted, using the weighted percentage method statistics, obtained primary liver cancer with portal vein tumor thrombus in the dialectic of traditional Chinese medicine Chinese medicine sub-type and common use of the law.Results:l.This study included a total of 28 about the Chinese medicine for treatment of advanced primary liver cancer randomized controlled trials, the use of Meta analysis of traditional Chinese medicine for treatment of advanced hepatocellular carcinoma evaluated:Chinese medicine treatment group compared to Western medicine control group, Efficient tumor:RR (relative risk)=1.54,95% confidence interval (1.34-1.76), stable tumor rate:RR (relative risk)=1.58,95% confidence interval (1.33-1.87), Quality of life (Karnofsky score) stable rate:RR(relative risk)=1.49,95% confidence interval (1.34-1.65),Half a year survival rate:RR(relative risk)=1.66,95% confidence interval (1.32-2.09); Distribution of the four indicators, the overall effect of hypothesis testing, P<0.05, both statistically significant.2.Chinese medicine hospital in Zhejiang Province of primary liver cancer with portal vein tumor thrombus were analyzed retrospectively,162 cases were selected, using the weighted percentage method statistics, Primary liver cancer with portal vein tumor thrombus involving the dialectical classification common are:spleen, liver depression, liver depression Spleen, Spleen wet storm (Yun/group), qi stagnation, yin deficiency, damp heat, blood stasis, qi stagnation of blood stasis, etc. Commonly used in traditional Chinese medicine are:Fuling,Baizhu,Miren,Zhuling,Jineijin,Shanyao,Bayuezha,Sheshecao,Taizishe,etc. There are several varieties of Chinese medicine involving:spleen Qi, Shugan Qi, heat detoxification, Huashi drugs, diuresis Shenshi, Qi drugs, blood circulation, etc. Common Syndromes and Chinese Medicine:Spleen Deficiency Syndrome:(including the spleen deficiency syndrome, spleen deficiency wet storm/Yun/group, Liver depression and spleen) Fuling,Baizhu,Miren,Zhuling,Jineijin,Shanyao,Bayuezha,Sheshecao,Taizishen, etc. Qi stagnation: (including air stagnation, qi stagnation) Chaihu,Yujin,Bayuezha,Baoshao,Chenpi,Maozhuacao,Chuanlianzi,Zhike,Muxiang,etc. Blood stasis:Yujin,Danshen,Yuanhu,Chishao,Zhiqiao,Ezhu,Taoren,Honghua,Shanling,Danpi,Chuanxiong,Yanhusuo etc. Damp-heat:(liver and gallbladder damp-heat, damp-heat syndrome): Chaihu,Baishao,Yinchen,Chuipencao,Jinqiancao,Haijinsha,Huangjin,Huanglian,Huangbo,Chuanpu,Cangzhu,etc. Yin deficiency:Shengdi,Shudi,Hongzao,Baishao,Beishashen,Nanshashen,Gouqizi,Maidong,Shihu,Wuweizi,Biejia,Qinghao, and so on.Conclusion:1. Chinese medicine treatment of advanced hepatocellular carcinoma evaluated: drawn:1.1 Chinese medicine treatment group was superior to Western medicine effective tumor control group, that is, combination of Chinese medicine or TCM treatment of advanced liver cancer tumors and efficient in the treatment of advanced liver cancer was superior to Western medicine;1.2 Chinese medicine treatment group stability and the rate of tumor control group was superior to Western medicine, namely, Chinese medicine or TCM treatment of advanced hepatocellular carcinoma with a stable rate in the tumor is superior to Western medicine for treatment of advanced liver cancer;1.3 Chinese medicine treatment group quality of life (Karnofsky score stability) and stability rates of the control group was superior to Western medicine, namely, Chinese medicine or combination of Chinese and Western medicine for treatment of advanced liver cancer in the quality of life (Karnofsky score stability) is superior to Western medical treatment of stable rates advanced liver cancer.1.4Chinese medicine treatment group survival rate was superior to Western medicine in six months the control group, that is, combination of Chinese medicine or TCM treatment of advanced liver cancer survival rate in six months is superior to Western medicine for treatment of advanced liver cancer. 2 Pairs of primary hepatocellular carcinoma with portal vein tumor thrombus retrospectively analyzed with2.1 Common Syndromes to:Spleen Deficiency Syndrome, Liver depression and spleen deficiency, spleen deficiency wet storm most common, followed by the liver Qi stagnation, Damp-heat, yin deficiency syndrome;2.2 Common types of traditional Chinese medicine:Qi and spleen, Shugan qi, dampness drugs, diuresis. Shenshi and so on;2.3 Common traditional Chinese medicine are:Fuling,Baizhu,Miren,Zhuling,Jineijin,Shanyao,Bayuezha,Sheshecao,Taizishen,Dangshen etc.
Keywords/Search Tags:Meta Analysis, Primary liver cancer, Traditional Chinese Medicine, Primary liver cancer with portal vein tumor, Thrombus syndrome analysis
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