The Change Rules And Its Significance For The Innate Immunity Reaction In Cord Blood's CD35 And CXCR4

Objective: To compare the difference of the blood cell innate immunity in cord blood and health adult , to compare the difference of the cord and adult erythrocyte control respective leucocyte innate immunity; Methods: To determinate the capability of the blood cell innate immunity in cord and adult adhering to tumor cell by using blood cell adhering to tumor cell method , and determinate the CD35 , CXCR4 expression on cord and adult in the condition of complete blood cell add tumor cell, complete blood cell add saline, complete blood cell add tumor cell without erythrocyte, complete blood cell add saline without erythrocyte. Results: The Rosette rate of the erythrocyte, lymphocyte,granulocyte innate immunity in cord blood adhere to tumor cell is lower than the health adult; the fluorescence intensity expression of CD35 on adult erythrocyte is lower than the cord blood, and the fluorescence intensity expression of CD35 , CXCR4 on adult lymphocyte and granulocyte is higher than the cord blood; the fluorescence intensity expression of CD35 , CXCR4 on adult and cord lymphocyte or granulocyte by adding erythrocyte is higher than the same without erythrocyte. Conclusion: The capability of the cord blood innate immunity is lower than the capability of the health adult blood innate immunity; the erythrocyte in adult complete blood cell and cord complete blood cell have enhancement property to the capability of the leucocyte innate immunity ,it become more obvious by added with tumour cell, and the regulating capability of the erythrocyte in cord complete blood cell is weaker than in adult complete blood cell.