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Evaluating The Value Of Postsystolic Shortening In Diagnosis Of Coronary Artery Disease By Strain Dopple Echocardiography

Posted on:2006-10-11Degree:MasterType:Thesis
Country:ChinaCandidate:C FengFull Text:PDF
GTID:2144360155470808Subject:Imaging medical ultrasound
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OBJECTIVE: to investigated the incidence and characteristics of postsystolic shortening (PSS) in healthy subjects and patients with coronary heart disease(CHD) using Strain Doppler Echocardiography(SDE), and the diagnostic value of PSS in CHD. METHODS: In 17 young healthy subjects, 31 patients with CHD, longitudinal myocardial deformation was measured. PSS were qualitatively and quantitatively analyzed and compared using ultrasonic strain. ROC curve was applied to evaluate the diagnostic efficiency of incidence of PSS for CHD and ultrasonic strain indexes for pathologic PSS.Results: The average incidence of PSS in CHD group and in multi—coronary disease was significantly higher than that in control group (P<0.01). under ROC curve area of CHD group and multi—coronary disease group were 0.832 and 0.911 respectively. Further, it approved that the best cut-off points might be 41.6% and 47.2% respectively, it was figured out that the sensitivety was respectively 80.6% and 84. 6%, the specificity of 76. 5% and 82. 4%. The average level of segment with normal contraction in CHD group was significantly higher than that in control group (P <0.01). The average level ofεpss and PSI in CHD group was significantly higher than that in control group (P <0.01).while, The average level of εsys and εpeak in CHD group was significantly lower thanthat in control group (vp<0. 01). under ROC curve area ofesys, £peak, epss and PSI were 0. 692> 0.640, 0.680, 0.779 respectively. CONCLUSION: PSS is a valuable predictor of CHD and our data indicate that pathologic PSS should be differentiated by coexiting exceeding PSI cutoff and incidence and, second by clinical situation.
Keywords/Search Tags:Coronary heart disease, postsystolic shortening, strain, Receiver operating characteristic curve
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