The Clinical Study Of Guchong Zhixue Decoction In Treating Hemorrhagic Period Of Dysfunctional Uterine Bleeding With Qi Deficiency And Blood Stasis Syndrome

Objective:To explore systematically the effect and the hemostasis principle of Guchong Zhixue Decoction(GCZXD)in treating dysfunctional uterine bleeding(DUB) with Qi deficiency and Blood stasis syndrome based on the theoretical and clinical research under the guidance of traditional and western medical theory. Method:60 patients were divided randomly into test group (30 cases, treated with GCZXD)and control group(30 cases, treated with Duanxue liu capsule).The hemostasis effect, the improvements of clinical symptoms and the density of endometrium,prothrombrn time(PT) and activated partial prothrombrn time(APTT),the platelet volume distribution width(PDW) and meanplatelet volume(MPV) ,the blood circulation, the serum level of fibrinogen degradationJ products(FDP) were observed.Results:GCZXD could improve clinical symptoms ofpatients obviously, and the difference was significant compared to control group. Meanwhile, the density of endometrium,PT,APTT and FDP were decreased,PDW and MPV were increased compared to those of the pretherapy, the blood circulation was improved greatly, and the difference was significant compared to control group that viscosity of plasma , viscosity of blood and ergthrocyte sedimentation rate were decreased, the fibrinogen was increased. Conclusin:GCZXD is an effective recipe in treating DUB with Qi deficiency and Blood stasis syndrome.The effect may be achieved through the operation of decreasing PT and APTT, increasing the level of PDW and MPV, improving...