Clinical Analysis Of Transient Ischemic Attack

Background Transient ischemic attack (TIA) is referred to one or more neurologic dysfunction caused by focal brain ischemia, with clinical symptoms lasting less than 24 hours, often several minutes to half an hour , without evidence of acute infarction. According to the data from northern California, within 90 days of TIA the stroke risk is 10.5% and the overall adverse vascular outcome (stroke, cardiovascular hospitalization , death, or recurrent TIA) risk is 25.1%. At present , there are controversy in the definition, standard of curative effect and the treatment effect of low molecular weight heparin. This article is to study these questions. Objective The aim of the present study is to study pathogenic mechanisms, age distribution, clinical features, CT and MRI characters of TIA and the treatment effect of low molecular weight heparin (LMWH). Methods 102 patients of TIA who were treated in our department were chosen in this study, clinical features, CT and MRI characters are analyzed, it is a preceding, non-random study. Standard of choosing: all the patients accord with diagnostic criterion of the fourth Chinese cerebral vascular conference; CT or MRI show no hemorrhage ;attack times are more than one; bleeding, decrease of blood platelet count, unnatural bleeding or coagulating time are excluded; Within recent 3 months, no operation, antico-agulation or reducing fibrinogen treatment, trauma history ;no liver and renal dysfunction. Grouping measure: All the patients are divided into 2 groups:comparison group 54 and treatment group 48. Regulating blood pressure, reducing blood sugar and aiming at symptoms, aspirin 50 mg, once per day taken orally and Ozagrel 160 mg once ivd are both done to all patients. Heparin LMW Sodium is added to the treatment group. Common situations between two groups like age, sex, state of an illness have no difference, they are comparable .Standard of curative effect: from using drug to 30 days, no attack is considered recovery; attack within 3 days and no attack is considered obvious efficiency; attack within 3~10 days and no attack is considered efficiency; attacking after 10 days is considered invalidation; cerebral infarction is considered deterioration. Statistics management: number data is examed X2, quantity is showed ±s,and examed by "t"method. And result P<0.05 is considered notability difference. Results Incidence of TIA is male>female ,incidence of internal carotid artery system and vertebra-basal artery system has no difference. The common symptom of internal carotid artery system in turn is limb...