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Research On The Representation Of The Effective Material Base Of Promotiong Blood Circulation And Arresting Bleeding Of Panax Notoginseng

Posted on:2007-09-24Degree:MasterType:Thesis
Country:ChinaCandidate:Y Y WangFull Text:PDF
GTID:2144360182492765Subject:traditional Chinese medicine chemistry
Abstract/Summary:PDF Full Text Request
This dissertation includes five parts .The first chapter shows a review about the progress of studies on Panax notoginseng(Burk.)F.H.Chen. The second chapter studies on the extracted term of the effective fractions of Panax notoginseng(Burk.)F.H.Chen. The The third chapter studies the determination of the effective fractions of Panax notoginseng(Burk.)F.H.Chen are established. The forth chapter introduces the characteristics of promotiong blood circulation and arresting bleeding of the effective fractions of Panax notoginseng(Burk.)F.H. Chen and the pharmacokinetics studies of their best compound. In the last chapter ,"The finger prints"of effective fractions of Panax notoginseng(Burk.)F.H.Chen and their best compound were established by HPLC.Chapter 1 Documents about the research progresses in the chemical constituents and pharmacological activites of Panax notoginseng(Burk.)F.H.Chen as well as other hemostatic Chinese medicine were summed up and analyzed, 76 references were cited.Chapter 2 To optimize the technology of extracting the effective fractions from Panax notoginseng(Burk.)F.H.Chen. With as criterions, the water extraction and ethanol extrac saponins and combined amino acids tion technologies of extracting the constituents of Panax notoginseng(Burk.)F.H.Chen were compared by HPLC and VIS spectrophoto- metry;and the L9(34)orthogonal experimental design was used to optimize the conditions of the ethanol extraction technology. As a result, the conditions of the ethanol extraction technology of extracting the constituents from of Panax notoginseng(Burk.)F.H.Chen were A2% ethanol, B3hours of reflux, C3-fold solvent and D1times of extraction.Observing the absorption faction with the amount of saponins ,Ginsenoside Rg1, Ginsenoside Rb1and Panax notoginseng R1 of Panax notoginseng(Burk.)F.H.Chen on the five kinds of macro absorption resins. We draw the conclusion that the A type resin has the best absorptive ability on the separation and enrichment of saponins,Ginsenoside Rg1...
Keywords/Search Tags:Panax notoginseng(Burk.)F.H. Chen, the best extracted term, qualitative and quantitative analysis, promotiong blood circulation and arresting bleeding, pharmacokinetics
PDF Full Text Request
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