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Genistein Suppresses In Vitro Invasion And Metastasis Of Human Hepatoma Cells SMMC-7721

Posted on:2007-10-19Degree:MasterType:Thesis
Country:ChinaCandidate:Y TianFull Text:PDF
GTID:2144360185452809Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
It is known to all that primary carcinoma of the liver is a tumor which arises from hepatocyte or biliary epithelium. The most common type of primary liver cancer is hepatocellular carcinoma. Hepatocellular carcinoma is the most common internal malignancy and an important cause of death in China. Every year there are about 110,000 people who died from primary carcinoma of the liver in our country. Moreover, the morbidity is rising in the world. The disease is threatening people's health and life. Up to now the etiopathogenisis and pathogenesis of primary carcinoma of the liver cannot be affirmed completely. It relates to synthetic action of several factors. Exairesis is the best radical cure to primary carcinoma of the liver at present. Unfortunately, most of patients have missed the opportunity to resect the tumor when they acquire the final diagnosis. The main reason is that it has developed intrahepatic or distant organ metastasis. It will lead to higher recrudescence. Accordingly, it is very important to seek an effective medicine to treat primary carcinoma of the liver, to improve the prognosis and to elevate the quality of life. Nowadays the predominant medicines for chemotherapy are most of cytotoxic drugs that have great side reaction. Therefore,...
Keywords/Search Tags:genistein, hepatoma, invasion, metastasis, matrix metalloproteinase-2, matrix metalloproteinase-9
PDF Full Text Request
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