The Expression And Its Clinical Significance Of PTEN And Survivin In Ovarian Tumor

Ovarian tumor is an ordinary one in the gynecologic disease. At the initial stage of ovarian tumor, there is few symptoms and no perfect diagnose method, which leads to the highest death rate among the gynecologic malignancies at present. With the changing of the modern human surviving environment and the deeper understanding of the disease, Tumor Gene Academic has attracted more and more attentions to research.Recent research has shown that the inhibitors of apoptosis proteins survivin is the strongest death inhibitors gene. Because inhibiting death is good for tumor cell live, so survivin is also called live element. Due to the special character of the tissue distributing and the powerful function of resisting cell death, survivin has become a hotpot of the studying the tumor's initial cause and cure. PTEN is a kind of inhibit gene with active phosphatase and has the relations with many family syndromes. PTEN mutates frequently in many kinds of malignancy tumors and has high value to the tumor development. If we lucubrated PTEN, we could use it to inhibit cancer effectively.There was negative biology effect between PTEN and survivin although both of them took part in cell cycle control and cell death. Their functions to ovary and correlations were not distinct still. By examining and testing the expressions of survivin and PTEN in ovarian serous papilliferous carcinoma, ovarian boundary tumor, ovarian serous papilliferous cystadenoma and normal ovarian tissue, the research probed...