| AIM: Pulmonary fibrosis(PF) due to lung injury is one of lung destructive disease in clinic. Once PF is formed, it can led to functional disturbance of respiration and circulation and threaten patient's life. Now it's pathogenesis and treatment is still one of the keystone research area of many scientists around the world. Transforming growth factor-beta(TGF-β) is a key molecule in the progression of pulmonary fibrosis. It can stimulate the new blood vessel formation in vivo. TGF-β can also promote maturation of pericyte and play an important role in the development of blood vessels. Vascular endothelial growth factor (VEGF) is the specific mitosis progenitor of endothelial cells, it can promote the proliferation and differentiation of endothelial cells, VEGF may also induce and form mass neonatal blood vessels. These two kinds of cell factors are correlate closely with repair of...
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