Significance And Changes Of Myocardial Injury Markers In Patients With Percutaneous Coronary Intervention

Objective Percutaneous coronary intervention (PCI) is a technique for cardiac intervention treatment in revascularization of coronary vessel. The use of PCI in patients with coronary heart disease (CHD) has expanded dramatically over the past three decades. With the evolution of operator experience and equipment design, procedural mortality and the need of emergency coronary artery bypass graft surgery (CABG) is occasional, but procedural myocardial injury is still the common complication. The etiology of post procedural myocardial injury is not clear. It is reported that side branch occlusion ,transient coronary spasm, coronary microembolization or intensity of procedure itself are responsible for increased levels of cardiac injury markers .Today ,the cardiac markers of creatine kinase MB(CK-MB), cardiac troponin I(cTnI) ,cardiac troponin T(cTnT) and myoglobin (Mb)are used to examine the myocardial injury. Many researchers have different opinion on the relationship between the increase of markers and prognosis. The prognosis includes adverse cardiac events such as sudden death, myocardial infarction and once more revascularization. Ischemia modified albumin (IMA) is a new myocardial injury markers in the medical field .However, it is less studied in patients of post-PCI .To compare the sensitivity and specificity of three markers(IMA, cTnI, CK-MB), to study the factors associated with elevated markers and the clinical outcomes after PCI and to evaluate the possible effects on...