The Study Of Expression Of HIF-1α As Well As Its Relationship With Expression Of Bax And Bcl-2 In Esophageal Squamous Cell Carcinoma

Esophageal carcinoma(EC) is a kind of malignant tumor of digestive tract frequently with poor prognosis. About 310, 400 new cases of EC were diagnosed worldwide a year, more than half of which are lay in China. The data publicized by WHO in 1999 indicates that the EC mortality of Chinese is the highest in the world, especially in Henan province. In recent 50 years, the basic research and technologies of diagnosis being developed, but the pathogenesis and pathologic mechanism involved in EC are still unclear, neither is therapeutic response be improved significantly. To...