Budd-Chiari Syndrome

Background and objectivesThe Budd-Chiari syndrome(BCS) is a heterogeneous group of disorders characterized by hepatic venous outflow obstruction at the level of the hepatic venules, the large hepatic veins, the inferior vena cava(IVC), or the right atrium, which results in increased hepatic sinusoidal pressure and portal or inferior vena caval hypertension. With the development of image technique, more and more of the cases are reported. The distribution of the disease in China is mainly situated in Huanghe region, such as Shandong, Shanxi, Henan, Hebei, Jiangsu and Anhui Provinces, etc. It was often misdiagnosed due to its insidious onset with no typical symptoms at early stage, and the prognosis is poor, the 5-survival rate is less than if not be treated.Though the local pathologic process is complicated, the basic change of BCS is the formation of membrane and secondary to thrombus at the suprahepatic IVC. Membranous obstruction of the IVC(MOVC) is the most common cause of BCS; it accounts for up to 33% of all cases reported worldwide, but the proportion of MOVC in China may up to 50-70%.Treatment of MOVC using of the diameter 30mm balloon catheter proved to be simple, safe and effective with microtrauma and low expenditure. The symptoms of most patients could be resolved within 2 months following PTA. The main factor influencing the long-term efficacy was restenosis, and the recurrent rate ranged form...