The Experiment Of Induce And Differentiation Mesenchymal Stem Cells Into Bone Cells And Building Tissue Engineering's Bone Tissue

Objective: The bone tissue engineering repair and regenerate bone through osteoblast generation and induce differentiation as well as growth living bone tissue in vivo vitro. The seeds cell and base material is the main investigative content of tissue engineering. Mesenchymal stem cells is a kind of multi-directional differentiation potency cell and can differentiate into osteoblast, chondrocyte, tendon, adipocyte, marrow stroma cell, vascular endothelial cell and nerve cell under specific condition, it was general all purpose seeds cell in bone tissue engineering investigate also because of easy to obtain and generation this cell. The base material is the basic framework and metabolism site of adherent cell, it form and function have direct influence on the tissue form and function construct by itself. The objective of this study is to investigate the contribution and characteristic of bone marrow mesenchymal stem cells as seed cell and the nanometer crystal hydroxyapatite collagen material as scaffold material in bone tissue engineering also in repairing bone defect.