The Effects Of Extraction Of Radix Isatidis On Immunological Function And Influenza Virus (FM₁) Strain In Kunming Mice

Aim: To study the strengthening function of extraction of Radix isatidis on immune system in Kunming mice and the antiviral effects of it on influenza virus (FM₁) in mouse pneumonia caused by FM₁ virus. Method: Extraction of Radix isatidis was intraperitoneally injected to Kunming mice, indices of immune function of mice were measured. FM₁ virus was dropped nasally in Kunming mice, the antiviral effects of Radix isatidis were observed. Result: Spleen index of the Radix isatidis group compared with control group was increased (p<0.05) . SI of T and B lymphocyte and the rate of RBC-C₃bR of the Radix isatidis group was all increased significantly compared with controlled group (p<0.01) . The rate of RBC-IC of that group compared with controlled group was decreased greatly (p<0.01) . There was no obvious difference of thymus index among groups (p>0.05). Compared with negative group, Lung index of the Radix isatidis group was decreased (p<0.05). The degree of change in weight of that group was higher than that of negative group (p<0.05) . Conclusion: Radix isatidis has strong strengthening function on immune system in Kunming mice, it's enhancing function on red cell immune adherence (RCIA) is extremely significant. Moreover, it also has antiviral effects on influenza virus.