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BMSC And FG Compound Repair Obsolete Joint Cartilage Damage Experimental Study

Posted on:2007-01-12Degree:MasterType:Thesis
Country:ChinaCandidate:J W LiFull Text:PDF
GTID:2144360185988459Subject:Bone surgery
Abstract/Summary:PDF Full Text Request
Objectives: 1. In the rabbit femoral condyle facies articularis manufacture articular cartilage damage animal model, the research different time, the damage size to the rabbit articular cartilage influence obsolete fibrosis situation, repair the experiment for the preparation obsolete articular cartilage damage animal model and the later period to provide the research foundation. 2. FG the load in vitro raise BMSC by organize the project method using may the injection textile fiber protein adhesive from the body marrow matrix stem cell to construct may the injection organization project cartilage damage repair implant the thing, the observation seed cell in material growth situation, understands two melting. 3. By the animal the repair material which constructs from body BMSC compound FG, separately carries on the repair control experiment to the obsolete articular cartilage damage model and the fresh articular cartilage damage model, by compares two group models the repair effects. Through the obsolete articular cartilage damage and the fresh articular cartilage damage animal model repair control experiment, for on clinical the repair method which gets sick regarding the obsolete cartilage damage enhances the new mentality.Methods:1. Rabbit obsolete articular cartilage damage animal model preparation: The health 6 weeks ages New Zealand big white rabbit, is female and male does not limit,...
Keywords/Search Tags:Obsolete, Cartilage defects, Bone marrow stromal cells, Fibrin glue, Repair
PDF Full Text Request
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