| [Objective] To evaluate the value of diffusion weighted magnetic resonance imaging in diagnosis and differential diagnosis of focal liver lesions.[Method] Diffusion weighted MR imaging and measurement of apparent diffusion coeffient (ADC value) were performed in 36 normal cases , 98 patients with172 local hepatic lesions( including hepatic cyst 57, hemangioma 39, hepatic carcinoma 32, metastasis 44) .And ADC values were calculated.. The b values were 0, 50, 500. T1WI, T2WI was performed in all livers. And multiphase dynamic enchancement was performed in 75 patients to observe dynamic contrast-enchanced change of the lesions.[Result] The average ADC values of focal hepatic lesions with lower b value(0,50) were significantly higher than that with higher b value(0,500). except hepatic cyst . when b=50 s/mm2, average ADC values of hepatic cyst, hemangioma, hepatic carcinoma and metastasis were (3.71±0.30)×10-3mm2/s, (7.74±0.74) ×10-3mm2/s, (5.16±0.57) ×10-3mm2/s, (4.94±0.45) ×10-3mm2/s. when b=500 s/mm2, average ADC values of hepatic cyst, hemangioma, hepatic carcinoma and metastasis were(3.35±0.31) ×10-3mm2/s, (1.72±0.20) ×10-3mm2/s, (1.09±0.21) ×10-3mm2/s, (1.18±0.14) ×10-3mm2/s. whether lower or higher b value, the average ADC value of malignant masses(hepatic carcinomas, metastasis) was significantly different from that of hepatic cysts and hemangiomas(P<0.001). yet, the ADC values of metastatic tumor overlapped with those of hepatic carcinoma. In routine MRI, most of liver masses showed low signal in T1WI and high or little high signal in T2WI. In dynamic contrast... |
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