Study On The Immune Mechanism Of Mifepristone Used For Medical Abortion

Objectives:Through observing morphological change ,the effect of mifepristone on the expression of LIF,VEGF in human villous trophoblasts and the number of Hofbauer cell in human villous stroma during the early pregnancy , explore the immune mechanism of mifepristone used for medical abortion from the viewpoint of the Th₁/Th₂ balance .Methods:1. The morphological features of mifepristone group and control group was studied by hematoxylin-eosin staining .2. Using immunohistochemistry and image analysis technique to test the expression intensity of LIF,VEGF in human villous trophoblasts and the number of Hofbauer cell in human villous stroma during the early pregnancy of 20 women ,upon whom medical abortion by means of mifepristone was performed (mifepristone group). 20 artificial abortion women were taken as the controls (control group).Results:1. Villous structure of mifepristone group was complete during the early...