| Objective: To evaluate the expression and localization of hnRNP A2/B1in endometriosis.Methods: Samples were obtained from three normal proliferate-stageendometria of young married and healthy women, three ovarianendometriosis and three eutopic endometria of three patients. Theexpression of hnRNPA2/B1 was examined by immunohistochemistry andWestern blot with a specific polyclonal antibody.Result: hnRNP A2/B1 was located in the nucleus of both epithelialglands and stroma. The expression level of hnRNP A2/B1 in theendometriotic tissues and the eutopic endometria of patients withendometriosis were weaker than those in the normal endometria(bothP＜0.05).The difference between the endometriotic tissues and eutopicendometria were insignificant (P＞0.05). Conclusion: hnRNP A2/B1 may play an important role in thepathogenesis of endometriosis.
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