Effects Of Reactive Velvet On Bone Marrow Suppression And Immunologic Function Caused By Chemotherapy

The study investigated effects of reactive velvet on bone marrow suppression and immunologic function caused by chemotherapy. In experimental studies, according to random and contrasting principle, experinental mice were divided into six groups, named or blood film group,small dose reactive velvet group, big dose reactive velvet group, ordinary reactive velvet group, the normal group, the model group, the model mice of xuexu were treated by CTX, to observe the change of markers, such as leukocyte total count in peripheral blood, egg protein antibody, IL-2,to investigate the effects of bone marrow blood function and confrontation of disappearing in bone marrow blood, and immunologic function. In clinical research, according to random and contrasting principle, breast cancer women were divided into two groups(CAF group,CAF plus velvet group), by some markers, such as leukocyte total count in peripheral blood, T cell subpopulation (CD₄⁺,CD₈⁺ and CD₄⁺/CD₈⁺), cytokine IL-2. The study aimed to research how reactive velvet influenced on leukocytopenia and the fall of immunologic function after chemotherapy.Experimental studies showed big dose reactive velvet group superior to the model group (P＜0.01), al so superior to other groups (P＜0.05; P＜0.01),and there hadn't much difference between other groups (P＞0.05).The reactive velvet can resist bone marrow suppression and improve immunologic function caused by chemotherapy and decrease side reactions of chemotherapy. To sum up, reactive velvet had the action of regulating organism from immunity and hematopoiesis respects, thereby clinical curative effects were improved markedly, reactive velvet was an ideal medicine to treat leukocytopenia.