Ultrasonic Thermotherapy In Tumor Treatment Temperature Fieldresearch And Two Kinds Of Different Laboratory Method Temperature Field Survey

The malignant tumor is a serious disease to the human health. Its treatment methods still mainly depended upon radiotherapy, chemotherapeutics, brotherapy, laser fever, freezing and so on in the clinical treatment. These methods have certain limitation in the clinical practice. In the recent several dozens years, the ultrasonic wave is widely applied in the biology, the medicine domain, the ultrasonic thermotherapy in clinical more and more becomes one effective method to the treatment tumor. The ultrasonic energy is one kind of mechanical energy, the partial energies are organized to absorb transform into the heat energy when it disseminates in the organization, causes the organization temperature increment. The ultrasonic wave has three primary aspects to cause heat energy: (1) ultrasonic vibration can the transform to heat engey when itsends through medium; (2) medium particle causes the temperature increase in the center because its periodicity contraction, this kind temperature increase in the center is due to the ultrasonic wave compression phase; (3) in different organization's dividing line part formation, because organizes acoustic impedance is different in the organization lamination, will have the reflection to form the standing wave, will cause the intermolecular relative motion to have the friction to form the heat, that will has the local temperature ascension in corresponding hits the mark with the anti-node. Primary factor forms hot. Medium's absorb is primary factor to formation hot in these factors. The different organization to the sound absorption is not same, produces hotly is not same. The absorption is related with the medium internal friction, the heat conduction as well as the molecular structure and so on. These three kinds of factors are deciding the absorption coefficient size.The tumor ultrasonic thermotherapy more and more receives the clinical treatment in recent years the value. The thermal reaction to the tumor organization's destructive effect is one of ultrasonic treatment tumor main mechanisms. The tumor necrosis critical temperature is 42. 5～43℃,The high energy focusing ultrasonic treats (HIFU) is seeks the treatment goal(tumor) through the B ultra diagnosis system,and moves the goal to the radiation focal point place.This place forms the strong sound field in the focal point place through the launch ultrasonic wave to cause to organize the elevation of temperature to achieve the tumor necrosis temperature to realize treatment goal. Treats effectiveness is obvious, and reduced the chemotherapy dosage in the chemotherapy coordination, reduced the poisonous side reaction in the present situation, and enhanced the treatment result.The ultrasonic thermotherapy usual has the side effect in the course of the treatment, the ultrasonic thermotherapy side effect mainly has scalding hot feeling, the ache, scalds (red spot, blister as well as ulcer) and the osseous ache and so on in the warming surface. The osseous ache is the common side effect, also is affects the thermotherapy full load warming the main limiting factor. The ultrasonic heating another side effect is the skin surface superheat.In the medical service has usually used appropriate readjustment water pocket domestic waters quantity method, causes the skin surface scalds (blister) the formation rate to reduce to lowly. In order to use the ultrasonic thermotherapy fully, in the treatment process also should consider the ultrasonic thermotherapy the side effect, enables the ultrasonic thermotherapy to achieve the biggest effectiveness.Thus it can be seen the ultrasonic thermotherapy key is the temperature control and the survey. Main method is lossless examination in temperature survey. The ultrasonic lossless temperature measurement mainly is causes the sound speed change as a result of the temperature change. The ultrasonic lossless temperature measurement method will divide into following several kinds according to the temperature measurement way: Reflect ultrasonic method; Shines through ultrasonic method; Finite element method; Ultrasonic image analytic method. In various ultrasonic lossless temperature measurement technologies, reflect ultrasonic method occupy mostly, beasuse this method carries on easily in the body experiment in clinical. The commonly used method has the ultrasonic echo time-shift method, the ultrasonic echo frequency-shift method, the ultrsasonic echo energy method, the ultrasonic echo time-frequency diagram division method, ultrasonic sound speed non-linear parameter method.The ultrasonic thermotherapy was considered one kind of non-invasive, promised and the most effective heating treatment the cancer method at present. But the ultrasonic thermotherapy still had some insufficiencies, mainly had following several aspect key question to need to solve: (1) Invariable focusing question: The different internal organs tumor spot is different, the tumor depth is different, the tumor of identical internal organs are also different from person to person, and the focusing adjustable transducer may be suitable for the different spot, different patient's tumor heating.(2) Clinical lossless temperature measurement: At present the common lossless temperature measurement method includes: Reflects ultrarsonic method, transmission ultrasonic method, the finite element method, the ultrasonic image analytic method. But each lossless ultrasonic thermometry develop very quickly but does not have one kind to be able to use in completely clinically, its method improvement also has very long way to go in future.(3) Further reduces the side effect and the consolidated curative effect: To compare with surgical operation, chemotherapy, radiotherapy and so on, side effect of the ultrasonic thermotherapy must be much smaller, but because the characteristics of the tumor itself multi-centers grow, the not obvious boundary as well as the cancer cell multiply quickly and so on, the partial treatment still to have the possibility to injure the small scope the normal tissue, and caused the whole body symptom. Therefore the reduction ultrasonic treatment the side effect to the cancer also is one of pending research question.The main purpose of this article is analysis the casuse of ultrasonic probe head elevates temperature, each kind of transducer parameter to the temperature influence using the value simulation and the temperature with each kind of parameter visual picture. Causes the temperature incresement of spleen using the ultrasonic wave illumination, simultaneously withdraws the ultrasonic echo signal, the analysis temperature with the time relations, has carried on the quota analysis to the temperature with the time relations, obtain the temperature and the time visual picture. So this article has mainly done the following several aspect researches:(1) Construction different organization temperature measurement model, discusses each kind of organization model the good with bad points, found suitable the clinical the temperature measurement model.(2)On basis biology isotropism biological tissue's heat conductivity equation through the computer technology computation biological tissue's temperature distribution, and found out related quantity with the biological tissue temperature. (3) Using computer software analysis kinds of transducer parameter and biological parameter that is related with the thermotherapy temperature. And using computer software drawed direct-viewing mapping analysis temperature parameter how to carries on to the temperature.(4) Using the different frequency the ultrasonic wave illuminate, observating relations frequency with the organization elevate temperature and surveying the organization the temperature. Using the different dual-frequency illuminate, observating relations frequency with the organization elevate temperature and surveying the organization the temperature, comparing with two method conclusions.