System Evaluate The Effect On Myocardial Protective Of Heart Operation With Beating Heart

Objective:To carry out a meta-analysis to evaluate the effect on myocardial protective of heart operation with beating heart.Methods:The analysis the levels of cardiac troponin(cTn-â… )used data from published trials in comparison with placebo supplemented where necessary by reference to the original trial reports.Result:Eleven trials were included,having there groups:inborn heart diseases(ASD,VSD,PDA,PS)five trials;Mitral valve replacement there trials;double valve replacement there trials.All included studies were inadequate in reporting randomization,concealment of allocation.Serum levels of cTn-â… was measured after anesthesia and at several times after aortic declamping or intra-cardiac manipulation finished,cTn-â… levels in beating heart group were lower than those in control group at several times after aortic declamping or intra-cardiac.Conclusion:Beating heart with mild hypothermia has better myocardial protection effects in heart operation.