Clinical Study On Relationship Among Syndrome Of Essential Hypertension In TCM, Blood Glucose, Blood Fat And Sensitivity Of Insulin

Objective: Essential hypertension(EH) is a sort of cardiovascular disease, it does great harm to people's health. Many clinical practices prove that Chinese medicine treatment for EH has its prevalence. Patient of EH often accompany with diabetes and hyperlipoidemia, which is also the common disease to harm human's healthy. The purpose of this subject is to investigate the relationship among syndrome of Eh in TCM, blood glucose, blood fat and sensitivity of insulin, in order to direct clinical treatment better and predict the most possible accompany disease earlier.Methods: 80 patients of EH were selected and classified into 4 types according to syndrome differentiation classified in TCM: the Liver-Fire exuberant syndrome, the phlegm-dampness abundant syndrome, Yin-deficiency and Yang-hyperactivity syndrome and the Yin-Yang dual deficiency syndrome. Statistics has been done in the level of blood fat, FBG, F-INS, ISI and HbAlc. All the data above were compared among the four syndromes.Result: (1) Comparison of the four syndromes' parameters of blood fat: The phlegm-dampness abundant syndrome's TC&TG were higher than the normal group. the difference among them is significant (P＜0.05). The phlegm-dampness abundant syndrome's TG were higher than the other three syndrome (P＜0.05).(2) Comparison of the four syndromes' parameters of FBG, F-INS and ISI:①The FBG, which is of the Liver-Fire exuberant syndrome, the phlegm-dampness abundant syndrome, Yin-deficiency and Yang-hyperactivity syndrome, is higher than the normal group(P＜0.05).②The F-INS, which is of the Liver-Fire exuberant syndrome, is higher than the other three syndrome and the normal group(P＜0.05). Compared to the normal group, The ISI, which is of the four types of EH, is significant(P＜0.05), the sequence of sensitivity of insulin among the four types of EH is the Yin-Yang dual deficiency syndrome＞Yin-deficiency and Yang-hyperactivity syndrome＞the phlegm-dampness abundant syndrome＞the Liver-Fire exuberant syndrome.(3) Comparison of the four syndromes' parameters of HbAlc: there's no statistics difference between the four types of EH and the normal group (P＞0.05).Conclusion: The data shows that insulin resistance resides in the each type of EH. IR&HI are main contained in the Liver-Fire exuberant syndrome, among the syndrome of EH, the advance of TG is main contained in the phlegm-dampness abundant syndrome. The blood fat and ISI can become the refindex of syndrome differentiation clssified in TCM.