| Objective:To evaluate the changes of microcirculation on ischemia reperfusion injury of extremities and the pyotective effects of huoxue pellet. Methods:58 patients were devided into two groups.Huoxue pellet was applicated in experimental group instead of saline in control group after ischemia and reperfusion .The changes of microcirculation were observed. Results:After 4hrs ischemia and 2hrs reperfusion of limb in control group:blood flow slowed down.Serious no-flow phenomenon,erythrocyte aggragation,large amounts of neutrophil-endothelial adhesion and white microthrombosts were observed in microcirculation.in experimental group:Microcirculation disturbances were alleviated. Conclusion:Huoxuepellet could alleviate ischemia reperfusion injury of extremities by improving microcirculation. |
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