The Influence In SP Levels In Brain-gut Axis Of ESDR By Atractylodes Macrocephala And Poria Cocos And The Experimental Study Of The Theory Of Meridian Tropism

Objective: To discuss the theory of meridian tropism from NEI network theory , we use the traditional Chinese medicinal animal model and study the effects of three kinds of herbs on SP levels in brain-gut axis. Methods: we used ESDR and observed the effects of three kinds of herbs on the D-xylose content of serum, the LDH activity of muscle, SP levels in brain-gut axis. And then we process these data with stepwise regression analysis to study the relativity between regulation of brain-gut axis and attribution to the spleen meridian. Result: Atractylodes macrocephala, Poria cocos and Gastrodia tuber have different effects in the experiments of FSTGTAT. Atractylodes macrocephala has better effects than Poria cocos and Gastrodia tuber on the above indexes, and Gastrodia tuber has no effect on the LDH activity of muscle. Poria cocos and Gastrodia tuber have no effect on the D-xylose content of serum. Atractylodes macrocephala has a remarkable regulation on the level of SP. We presume that the attribution to the spleen meridian is correlated with the regulation of brain-gut axis. Conclusion: The uses of NEI network theory and stepwise regression analysis have certain value to research the theory of meridian tropism. To some extent, the experiment offer new method for the study of the theory of meridian tropism.