Evaluation Of Chinese Version Of EORTC QLQ-30 V3.0 Or Xinjiang Minority Patients With Cancer

Objective To study and research the EuroPean Organisation for Research and Treatment of Cancer Core Quality-of-Life Questionnaire-Core 30(Version 3) exam the quality of life for Xinjiang minority patients(Uygur and Hazakh)with cancer, study the acceptability and evaluate the reliability, validity and responsiveness to change. Method First we developed the Uygur,s and Hazakh ,s version by translation and back-translation and cultural adaptation the EORTC QLQ-C30 V3 Chinese version. Secondly we distributed these questionnaires to 415 minority cancer patients in the first affiliated Hospital of Xinjiang Medical Univerity and investgated thei quility of life. Then we repeat investgated 126 persons of those patients ,quality of life after two or three days. In addition to this, we investgated 45 patients ,quality of life after two weeks the third time. Finally, we evaluate the reliability, validity , responsiveness to change and acceptability of EORTC QLQ-C30 V3. Results (1) evaluation of reliability:a. consistency reliability:Cronbach,sαcoefficient of this questionnaire is 0.810. Cronbach,sαcoefficient of each domain is larger than 0.77 and smaller than 0.810. b. split-half reliability:The split-half reliability coefficient is 0.745. c.retest reliability:The test-retest correlation coefficients of all domains and overall scale all are larger than 0.7;The paired t-test indicated no statistically significant change between the first time and the second time (P>0.05). (2) evaluation of validity:The correlation coefficients between all domains and the overall scale all were larger than 0.5. 3 commons factors were extracted and the cumulative variance was 59.04%. (3) evaluation of responsiveness:The paired t-test indicated have statistically significant change between the first time and the third time (P<0.05) apart from emotional function, social function and financial straits item.(4) evaluation of acceptability:The recovery rate is 95.73% and the complete rate is 97.86%. The time of complete questionnaire all less than 20 minutes. Conclusion The Uygur,s and Hazakh ,s version by translation and back-translation and cultural adaptation the EORTC QLQ-C30 V3 Chinese version are reliable, valid , sensitive and feasible . It have reference value to estimate the quality of life Xinjiang minority patients with cancer.