Detection Of Retinal Nerve Fiber Layer Thickness Of Primary Open Angle Glaucoma By Optical Coherence Tomography

Objective:To detect the retinal nerve fiber layer(RNFL) thickness around optic disc among normal and primary open angle glaucoma(POAG) eyes by optical coherence tomography(OCT) and analyze.Methods:The study enrolled 3 groups:normal group, and POAG group.Subjects underwent regular ocular examination,perimetry,detection of RNFL thickness using OCT,and analyze statisticly.Results:The study enrolled 148 cases(294 eyes) in normal group,and 48 cases(89 eyes) in POAG group.Statistic difference were observed in temple,superior,nasal,inferior,and average RNFL thickness among normal group and POAG group(P=0.000).Using the multiple linear regression analysis with age(X₁),intraocular pressure(X₂),mean defect(X₃),course(X₄)and mean RNFL thickness(Y),equation was built up:Y=107.691-0.349X₁+1.709X₃-2.702X₄. Conclusion:Detection RNFL thickness by OCT conduces to know and monitor the damage of RNFL in POAG,and OCT is a kind of auxiliary method for POAG valuably, potentially,and objectively.