To Study The Apoptosis Of The Inhibition Of Saikosaponins On Lung Adenocarcinoma A549

Objectives: To study the mechanism of the inhibition of saikosaponins on lung adenocarcinoma A549。METHODS:To observe the inhibition of saikosaponins on lung adenocarcinoma by growth curve, detect apoptosis by TUNEL, detect express of P53 by immunohistochemical.RESULTS: Different concentrations of saikosaponins all showed concentration-dependant and time-dependant inhibition action on lung adenocarcinoma A549 cells, the express of P53 is coincident。CONCLUSION:The inhibition action of saikosaponins on lung cancer A549 cells is attributed to induce apoptosis。...