Clinical Study On Advanced Breast Cancer Treated By The Method Of "Shu Gan Jian Pi" Combined With Chemotherapy

Objective: aim at the majority of later period breast cancer patient, the sentiment will is impeded ,spent-up the liver spleen, the liver spleen injuries suffered by both sides in the course of time, the stagnation of qi and blood stasis, gathering the phlegm to ferment the poison, the stasis poisonous will tie mutually the pathogenesis characteristic, will draw up smoothing zhe liver and strengthening the spleen, strengthening anti-pathogenic qi and replenishing qi for mainly therapeutic method---"shu gan jian pi fang", the coordinate chemotherapy, the observation the cooperation of Chinese and Western medicine treatment later period breast cancer curative effect. Methods: 45 example IIIB or IV issue of breast cancer in hospital patient, divides into two groups stochastically, in which observation group 24 examples, the comparison group 21 examples,two groups give the TA plan chemotherapy, the observation group add taking"shu gan jian pi fang"along with syndrome modifications.Observes two chemotherapy treatment courses after continuously around, treats the tumor focus of infection, the symptom, quality of life grading, the immunity function, tumor designated object CEA, the CA153 change and the poisonous side reaction appearance situation compared with two groups.Results:"shu gan jian pi fang"modifications coordinating chemotherapy may improve the patient majority of clinical symptoms, improves the quality of life, reduces the blood poisonous side reaction, enhances organism immunity function, reduces tumor designated object CEA, the CA153 level, but there is non-significance difference at reducing light illness stove aspect comparing with the pure chemotherapy group ,to the liver, the kidney function harm are not all obvious. Conclusion:"shu gan jian pi fang"modificationgs coordinating chemotherapy may enhance breast cancer patient organism immunity, enhances the chemotherapy curative effect, reduces the side effect, the function which the suppression tumor progresses, improves the patient symptom, improves the patient quality of life, treats one of later period breast cancer effective methods.