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The Clinical Study On Pathological Typing Of 456 Ovarian Tumors

Posted on:2010-02-07Degree:MasterType:Thesis
Country:ChinaCandidate:R HuangFull Text:PDF
GTID:2144360272495772Subject:Clinical Medicine
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Objective:Ovarian tumors are frequent tumors in gyanecology and the ovarian cancer is one of the three largest malignant tumors of female genitalia. For the past few years, there is a good development on the research about the diagnose and therapy of ovarian tumor, according to the pathology typing of ovarian tumors, my research is mainly to discuss the character of morbidity, the distribution of all kinds of ovarian tumors in different age groups and the chosen of specific treatment protocols with our hospital's practical together.Method:Retrospective analyze the postoperative pathology information of 456 patients whom were treated by operation in the first houspital of JinLin University during Jan.2004 and Dec.2008, and analyze the information by statistic methods, like chi-aquare, T test and so on.Result:(1)The percentage of benign ovarian tumor in child-bearing period female is largest among the three age groups ,is 85.5% whlie the percentage is smallest in menopause female with 78.3%.In the ovarian cancer, the percentage of menopause female is largest 27.8%,while the smallest in child-bearing period female with 8.6%. As for borderline tumor,mostly in the child-bearing period female with the percentage of 5.9%,there is statistically significance in the difference;(2)The percentage of epithelium tumor is respectively 55.1%,57.6% and 73.2% in the three age groups,the percentage of sex cord-stromal tumor is respectively 6.1%,8.9% and 21.7% and the percentage of germ cell tumor is respectively 38.8%,33.5% and 5.1%.It is suggested that the main tumor in adolescence patients is germ cell tumor while epithelium tumor and sex cord-stromal tumor in menopause patients.It is clear that the incidence of epithelium tumor and sex cord-stromal tumor are rising with the ages increasing,while the incidence of germ cell tumors are in the downtrend.(3)The percentage of benign epithelium tumor and sex cord-stromal tumor is largest in menopause female in the 378 benign tumors, is 72.2% and 22.2% respectively.However,the percentage of germ cell tumor is largest in adolescence.It is suggested that the main benign ovarian tumor is germ cell tumor in adolescence while epithelium tumor and sex cord-stromal tumor in menopause female;as for the particular pathological typing, the main benign tumor is mature teratoma in adolescence and child-bearing period female while in menopause female mainly is the serous cystadenoma.,but it has no statistically significance.(4)The percentage of advanced stage ovarian cancer is rising along with the age increasing.(5)In this sample, the ages of ovarian tumor are in a range from 4 to 77years old. The ages of patients with benign ovarian tumor and malignant tumor are respectively in the range from 4 to 77 years old and 9 to 72 years old. Combining with the pathology typing,the mean age of benign epithelium tumor is 40.4 years old, the malignant epithelium tumor is 47.3 years old and the borderline epithelium tumor is 28.3 years old..The mean age of ovarian cancer is seemed to be younger than in past. (6)There is no statistically significance in the difference of living region distribution among the patients with different ages and different pathological typing of cvarian tumor. (7)The therapy of benign ovarian tumors: adolescence usually take the operation of divest of ovarioncus, menopause female usually take the operation of hysterectomy and affected adnexectomy; (8)The therapy of malignant ovarian tumors: adolescence shoule take the operation of reserving the function of procreation and go on with chemotherapy or radiotherapy after the operation;menopause female should take the radical surgery and go on with appropriate courses of chemotherapy or radiotherapy after the operation; (9)There is no statistically significance in the difference of living region distribution among the patients with different ages and different pathological typing of ovarian tumor.Conclusion:(1)The percentage of benign ovarian tumor and malignant ovarian tumor is respectively largest in child-bearing period female and menopause female;(2)The main ovarian tumor are germ cell tumors in adolescence patients while epithelium tumors and sex cord-stromal tumors in menopause female.It is clear that the incidence of epithelium tumor and sex cord-stromal tumor are rising with the ages increasing,while the incidence of germ cell tumors are in the downtrend.(3)The main benign ovarian tumors are germ cell tumors in adolescence while epithelium tumor and sex cord-stromal tumor in menopause female;as for the particular pathological typing,there is no statistically significance among the different pathlogical typing of different age group. Adolescence with benign ovarian tumors usually take the operation of divest of ovarioncus and menopause female usually take the operation of hysterectomy and affected adnexectomy;(4) There is no statistically significance in the difference of different pathological typing,but the percentage of advanced stage ovarian cancer is rising along with the age increasing.As for the therapy of ovarian cancer,adolescence shoule take the operation of reserving the function of procreation and go on with chemotherapy or radiotherapy after the operation ,while menopause female should take the radical surgery and go on with appropriate courses of chemotherapy or radiotherapy after the operation;(5) In this sample, the mean age of benign epithelium tumor is 40.4 years old, the malignant epithelium tumor is 47.3 years old and the borderline epithelium tumor is 28.3 years old.There is statistically signficence in the difference.The mean age of ovarian cancer is seemed to be younger than in past.(6)There is no statistically significance in the difference of living region distribution among the patients with different ages and different pathological typing of ovarian tumor.
Keywords/Search Tags:ovarian tumor, pathology, histological typing, age distribution
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