The Investigation On Urinary Iodine And Thyroid Disease In Pregnant Women In Guang Xi Beihai Area

OBJECTIVE To study the prevalence of thyroid disease in pregnant women in GuangXi Beihai Area and the influence on the thyroid disease.And to provice the science theory on the iodine supplement rationally.METHODS To survey the prevalence of thyroid disease in the pregnant women in GuangXi Beihai Area.Blood samples from 693 pregnant women were randomly collected and assayed for FT3,FT4,TSH and urinary iodine at The No.9 Affiliated Hospital of Guangxi Medical University from August 2007 to August 2008 ,TPOAb and TRAb were detected in those doubted suffer from the autoimmune thyroid disease.RESULTS The median urinary iodine was 442.57μg/L in the pregnant women in GuangXi Beihai Area,Values lower than 50μg/ L were found in 6.1 % of the subjects,and Values lower than 100μg/L were found in 17.8 %,The prevalence of hyperthyroidism,subclinical hyPerthyroidism, hypothyroidism, and subclinical hypothyroidism were respectively 1.01 %,5.92 %,1.30 % and 4.76%. U-I positively correlated with TPOAb and TSH,but negatively correlated with FT4.CONCLUSION The pregnant women's iodine supply overdose in Guang Xi Beihai Area.The thyroid diseases which the pregnant suffered from in Guang Xi BeiHai Area were mainly Subclinical Hyperthyriodism and Subclinical HyPothyroidism,and the reason is hypso-iodine possibly. So we suggest pregnant women in Guang Xi Beihai Area should reduce to eat high-iodine food such as sea tangle, laver and sea food. Control MUI lower than 100μg/L as far as possible.It should be monitored closely in the pregnant women with Positive TPOAb.