Clinical Research Of Di Huang Shen Ze Ke Li For Treatment Of Benign Prostatic Hyperplasia

Benign prostatic hyperplasia(BPH) is a common disease and frequently occurring illness in older men. It is reported that BPH occurs in more than 50% of men over 60 years, 15% - 30% of patients causing lower urinary tract symptoms (LUTS). Recently with the population aging the global average expectation of life is in-creasingly extending. Meanwhile, with the progress on etiopathogenisis and development of BPH and the improvement in the diagnosis and treatment, the immense medical problems involving BPH are increasingly worldwide at an alarming rate. In traditional Chinese Medicine (TCM), the efficiant treatment of BPH (named Long Bi in TCM) have developed for thousand years.Dept. of Andrology of Xi Yuan Hospital combines pathogenesis of TCM with pathology of western medicine, advocating paying equal attention to deficiency of Qi and Blood stasis. Based on the pathogenesis feature above, the Di Huang Shen Ze Ke Li was prepared on the therapeutic principle of invigorating Qi and promoting Blood flow. Clinical observations have been proved that Di Huang Shen Ze Ke Li can reduce the IPSS, Qmax and residual urine volume, develop the quality of life and improve the dysuria symptoms.Objective: To observe the clinical effect on benign prostatic hyperplasia (BPH) treated by Di Huang Shen Ze Ke Li.Method: In clinical observation 80 patients from Dept. of Andrology, Xi Yuan Hospital were divided averagely into two groups at random: 40 patients in control group treated with Long Bi Shu (0.9g/d) and others treatment group with Di Huang Shen Ze Ke Li. The symptoms and sighs, the remark of IPSS, Qmax, residual urine volume and prostate volume were detected before treatment and after being treated for 3 months.Results: 70 patients were valid in total (36 in treatment group, 34 in control group). In the treatment group, the total effective rate was 77.8%, while the total effective rate was 64.7% in the control group. With Chi-square test, T-test and Ridit test (by SPSS 13.0), the difference between the two groups was significant (P<0.05), which show that the effect of Di Huang Shen Ze Ke Li is better than the control group in treatment. Remarkable decrease of IPSS in both groups after research while treatment group of Di Huang Shen Ze Ke Li showed better than Long Bi Shu in control group (P<0.01, P<0.05). Familiar results in comparison of Qmax, residual urine volume and the remark of the symptoms and sighs. The change of prostate volume in treatment and control groups was not significant (P>0.05). Side affect did not show up in both groups.Conclusion:â‘ The Di Huang Shen Ze Ke Li can obviously alleviate the symptoms and signs of the BPH, reduce the IPSS, develop the quality of life of the patients of BPH.â‘¡The Di Huang Shen Ze Ke Li can obviously reduce the Qmax, residual urine volume.â‘¢The results show that the effect of Di Huang Shen Ze Ke Li on the BPH was superior to that of Long Bi Shu.â‘£Side affect did not show up in Di Huang Shen Ze Ke Li group.