Marvelon Pill Zuogui Treatment With Adolescent Dysfunctional Uterine Bleeding (Liver Kidney-yin Deficiency Syndrome) Clinical Observation

Objective1.In theory,under the guidance of traditional Chinese medicine to find simple,convenient,economic,compliant,and more sustained treatment effect of adolescent dysfunctional uterine bleeding(liver kidney-yin deficiency syndrome) patients.2.Through clinical observations,the total effect from the treatment,vaginal bleeding,the patients with syndrome of the efficacy of hemoglobin before and after the change and after stopping to discuss the situation again with Zuogui Marvelon the effectiveness of pills in order to tie in with the left marvelon In the treatment of adolescent DUB pill(liver kidney-yin deficiency syndrome) in patients with bleeding and tune-week efficacy of the objective to provide a scientific basis.Methods1.Select adolescent patients with dysfunctional uterine bleeding 200 cases,all cases are fromhpril 2003-December 2007 in our hospital Emmeniopathy adolescent specialist out-patient trea tment of patients with dysfunctional uterine bleeding.All cases are in line with 2002 by the State Drug Administration issued a "clinical study of Chinese medicine guiding principles" (for trial implementation) of the diagnostic criteria.TCM kidney-yin deficiency of liver-type card.Treatment according to the order of succession were randomly divided into treatment group and control group,treatment group,100 cases,100 cases of the control group were compared between the two groups of cases bleeding time,bleeding the way,the degree of anemia,endometrial thickness, traditional Chinese medicine symptoms before treatment,after the Census and Statistics school examination,there was no significant difference(P> 0.05),comparable.2.Both groups were given oral marvelon(marvelon ingredients: Compound desogestrel,each containing ethinylestradiol 30μg; desogestrel 150μg),3,4 tablets / d,oral 2,3 points,only 3 d after the blood began to reduce every 3 d to reduce 1 / 3 to 1 / d maintenance dose,no blood 21 d after the withdrawal period,waiting for evacuation of uterine bleeding.Withdrawal bleeding the first five days of the beginning of the next cycle of medication,a marvelon day 1,only 21 days after the withdrawal of blood,three consecutive menstrual cycle.The treatment group taking control of bleeding during the service after oral pill Zuogui(Zuogui pill ingredients as follows:shudi,shanyao,gouqi,shanzhuyu,chuanniuxi, tusizi,lujiaojiao,guibanjiao),10g / time,3 times /day,nonmenstrual use;control group,not drugs,are three-cycle course of trea tment was 1.Close observation during treatment of patients with clinical symptoms of drug withdrawal in March,June,December outpatient or telephone follow-up review.Two follow-up 100%, respectively,during treatment to check their safety and efficacy of observation. 3.the total effect of clinical criteria:the light of the 2002 edition of "Chinese medicine treatment of dysfunctional uterine bleeding of the guiding principles of clinical research" to develop, recover:After the treatment,restoration of menstrual regularity more than six times;markedly:After the treatment,restoration of menstrual regularity greater than 3 times less than 6 times; effective:After the treatment,restoration of menstrual regularity less than 3 times or failure to restore menstrual regularity autonomy;invalid:can not use 72-hour blood signi ficantly reduce or stop,or course of treatment will be diverted to other treatment of persons.4.Statistical analysis methods:statistical software SPSS13.0 data for analysis.Measurement data using t test,X2 test with count data,with Ridit level data analysis.Results1.Zuogui Marvelon pills with the treatment of adolescent dysfunctional uterine bleeding(liver kidney-yin deficiency syndrome) Clinical cure rate of 80%,before and after treatment were significantly different(P <0.05).2.The treatment of clinical cure rate of 80%,total effective rate was 98%;the control group recovered 75%of the total effective rate was 97%,by Ridit analysis,we can see the efficiency of the two groups there was no significant difference(P> 0.05).3.The treatment group in improving dripping vaginal bleeding, dizziness,tinnitus,insomnia forgetful,waist,etc.腿软better acid,compared with the control group were significantly different (P <0.05). 4.Hemostasis treatment group the average number of days to 4.60±2.57 days,the control group the average number of days to stop bleeding for 5.06±2.65 days,compared the two groups no significant difference(P> 0.05).5.The two groups increase in hemoglobin after treatment were significantly different(P <0.05)6.The two groups after treatment DUB reproduction rate were significantly different(P <0.05).7.Two adolescent dysfunctional uterine bleeding medication non-toxic side effects,safe and reliable.ConclusionMarvelon Pill with Zuogui can improve adolescent dysfunctional uterine bleeding(liver kidney-yin deficiency syndrome) clinical symptoms,and sustained clinical efficacy.