| Bone metastases is the primary organ in the body of a malignant tumor through the blood circulation or the lymphatic system resulting from the transfer to secondary bone tumor,Chinese medicine is "Gubi","Yin Bi" category,Malignant complications are common,each can be transferred to the malignant tumor of bone,to one of breast cancer,thyroid cancer,lung cancer,is the highest incidence of bone metastases.And our patients die of cancer each year about 500 million people,after the death of cancer patients, autopsy in about 50%of cancer patients with bone metastasis was found,half of which are sick on the clinical symptoms.At present, the comprehensive treatment of bone metastases has become a major method of treatment,Chinese medicine in the treatment of bone metastases has become the main method of Chinese medicine in bone metastases treatment in the role and advantages,increasing domestic and international sector of the importance of tumor.Plan to have surgery,radiotherapy,chemotherapy,combined with Chinese medicine treatment in improving the quality of life of patients, radiotherapy and chemotherapy to reduce side effects,control of tumor metastasis and prolong the survival period of significant effect.In this study,since the two sides to be the basis of bone loose side,and the basis of clinical evidence with addition and subtraction,Mentor Professor Li Hangsen use years of clinical and effective.Custody of the parties follow the kidney marrow,Huoxue qi,removing the basic rules of pain.The prescription is composed of Psoralea corylifolia,drynaria fortunei,astragalus membranaceus,containing,barrenwort,radix rehmanniae,dried tangerine or orange peel,pangolin,oysters,ShiJian wear, liquorice.The psoralea corylifolia,Drynariae Bushen myeloid fill, the raising of strong bone bone;astragaloside added weak physical ;lucidum,epimedium,transfer level;pangolins,calcined oysters, Resolve the congestion,reduce pain,resist the cancer,soften the hard things,dissipate the mass;Chenpi dredge gas,reduce pain,and Win the spleen and stomach health;Licorice add Blood,to resolve drug toxicity were played on the gong uphold.PurposeThe purpose of this study from clinical observation of the powder of two bone united bisphosphonates observation the treatment of cancer patients with bone metastases General efficacy,for Clinical treatment of bone metastases in Chinese medicine to provide effective methods and theory.MethodSelected out-patient treatment at a Chinese medicine hospital in Hubei Province of bone metastasis of 30 cases of cancer patients, all patients were confirmed by histopathology or cytopathology has confirmed primary cancer,diagnosed by the imaging of bone metastases,and in strict accordance with the inclusion criteria to select cases.According to the sequence of the clinical treatment of patients and the compliance of Chinese medicine,30 patients were included in the treatment group and control group,15 cases in each group, two groups of patients at pre-treatment age,duration,number of metastatic lesions,pain classification aspects significant difference(P>0.05).Treatment group to one of two bone powder in the treatment of(mainly drugs,including Psoraleae 15g, Drynariae 15g,Radix Astragali 15g,Ligustrum lucidum 12g,Icariin 10g,shudihuang10g,Chenpi 15g,pangolin 12g,calcined oyster 12g, stone wear,see 12g,Radix Glycyrrhizae 6g),addition and subtraction with the disease,Peach kernel add much blood resistance,safflower,red sage root,Chinese angelica and other drugs;Dampness inside the condensate system very well add Banxia, system of Southern Star,Arrowhead Mountain,Polyporus,such as medicine;qi deficiency add very ginseng,Chinese angelica,red sage root,such as medicine;Cold condensation Yang Guizhi well or add cinnamon,fine Sim,monkshood and other drugs;add bidentata disease at lower limbs;disease in the lumbar,thoracic Dipsacus add;yanhu add severe pain element Cynanchum paniculatum, Pericarpium Papaveris,Zaocys snakes,centipedes and other drugs; do not want to eat add Atractylodes macrocephala,villosum.One day, decoction twice in two warm clothes.Fine in accordance with United Thai(manufacturing enterprises:Jiangsu Chia Tai Pharmaceutical Co.,Ltd.fine;Approval Number:State Yao Zhunzi H20041346; generic name:zoledronic acid injection) treatment,each 4mg(1 branch),with 100ml 0.9%sodium chloride injection diluted intravenous drip,drip of time not less than 15 minutes. Administration once every four weeks;the control group according to the Thai in the treatment of fine,more than two consecutive 3-month treatment,no pain medication during treatment.The two groups were observed in patients with major clinical effect, including the related signs and symptoms,pain grade,peripheral blood,liver and kidney function,blood calcium and the quality of life to improve the situation.ResultsHigher clinical efficacy is in treatment group.Treatment group has in improving the efficiency of pain was 86.7%,53.3%for the control group;the treatment group in reducing the occurrence of bone-related events have the efficiency of 93.3%,61.5%for the control group;the treatment group has lower transfer efficiency of recurrence was 86.7%,the control group was 40.0%;the treatment group to improve the situation in regard to the quality of life there is the efficiency was 86.7%,33.3%for the control group;above all by the statistical treatment,P<0.05,with statistical significance, and by the detection of peripheral blood,liver and kidney No obvious features such as side effects.Throughout the course of the study,no patients from group.ConclusionIn this study,starting from the TCM syndrome differentiation, often based on clinical Kidney injury myeloid Yishen Zhuanggu stand, Quyu Jiedu of law,and by promoting blood circulation,Qi,blood, spleen,clearing away heat and toxic and so on,to the two bone Powder United Zoledronic acid Injection treatment of bone metastases,two bone showed United Powder bisphosphonate treatment of bone metastases have a good synergy,at ease-related symptoms, reduce pain and improve quality of life of patients,control of tumor metastasis,more than one bisphosphonate treatment of bone metastases,and the course of the study does not appear obvious side effects.That traditional Chinese and western medicine for treatment of bone pain in metastatic carcinoma positive effects, clinical observation than a simple Western medicine therapy has certain advantages,it is worth to further explore the clinical and promotion.
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