| As a new type self-setting non-ceramic hydroxypatite artificial bone material, calcium phosphate cement has plenty good propert,Among which are fine biocompatibility,property of selfsetting,degenerating activity in corresponding with ossification,being able to be used for release-carrier of drag and bioactive factor,and so on.However,it still has demerits,such as,long time of setting,poor adhesion property,deficienty of strength,slowness of degradation.The application of calcium phosphate cement was limited.it is essential to improve the fuction of CPC。The aim of this research to investigate the effect of an effervescent-sucrose on the properties of calcium phosphate cement。The experent used sucrose particles that were mixed with CPC powder at sucrose/(sucrose+CPC powder) mass percentage of 0%,10%,20%,30%,40%。The samples were characterized by compressive strength,X-ray diffraction,SEM techniques and degradation in vivoo The result show:samples decreased on the mechanical properties and increased on the rate of macropore and total porosity,they were effected significantly among groups by added effervescent(P＜0.05)。The rate of macropore and total porosity of 30%CPC has 22.8%62.9%,respectively;40%CPC has 39.7%,70.3%;respectively;howver,it's compressive strength signifycantly decrea-sed from 5.4MPa to 2.6MPa。XRD indicated the transformation of apatite was promoted by increasing the effervescent。The biodegradation of samples had significant difference between 0%CPC and 30%CPC(P＜0.05),it demonstrated the CPC with macropore can promoted degradation and resorption。Conclusion:30%CPC has proper compressive strength,the rate of macropore and total proposity,and accelerate biodegradation and resorption,therefore,30%CPC could be novel biomaterials as an endo steal implant。...
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