The Effects Of Octacosanol Supplementation On Some Biochemistry Indexes In Athletes

Objective:In recent years octacosanol can cure all kinds of illness as the main research inside and outside of the country.There are very few reports about the effects of octacosanol supplementation on blood lipid metabolism,immune function,testosterone and cortisol in athletes, however,animal experiments shows that the capability of removing free radical and endurance tranning can be improved by octacosanol supplementation.Moreover,the immune function and sex hormone excreting can be accelerated.The study is focus on wrestling athletes and judoka taking three different dosages octacosanol supplementation in consecutive five weeks to observe the effects of octacosanol supplementation on blood lipid metabolism,immune function,testosterone and cortisol in athletes,which supples a certain academic foundation for octacosanol reseanable use.Methods:human experimentsThe athletes were divided into four groups:control,10mg octacosanol supplementation group(10mg group),20mg octacosanol supplementation group(20mg group) and 30mg octacosanol supplementation group(30mg group).Testing guidelines included body composition,blood routine detection,blood lipid,serum leptin,T lymphocyte and their subsets, testosterone and cortisol.Results:1.After octacosanol supplementation the weight,fat content,body fat percent and BMI of wrestling athletes and judoka is lower than before and 20mg dosage has the most influence on weight,fat content,body fat percent and BMI.2.After octacosanol supplementation the blood lipid of wrestling athletes and judoka has certain changes and the 20mg dose has better effect on HDL-C,the radio of HDL-C and LDL-C.3.After octacosanol supplementation the serum leptin of wrestling athletes and judoka is higher than before in other groups except 20mg group,which has contrary changes and is lower than control.The correlation shows that there is a significant positive correlation between serum leptin level and fat content,body fat percent,BMI and TG,while it has negative correlation with HDL-C.4.After octacosanol supplementation the white blood cells,CD3+ and CD4+/CD8+ of wrestling athletes and judoka is higher than before,and 10mg dosage has best effect.5.After octacosanol supplementation testosterone,the radio of testosterone and cortisol of wrestling athletes and judoka is higher than before,especially 20mg group.