Clinical Observation On Treatment Of Insomnia By Menopause With Geng Nian An Shen Decoction

Objective:To observe the effect of the Gengnian'anshen Decoction on patients with menopausal insomnia and to explore the mechanism of this treatment from the view of traditional Chinese medicine.Methods:60 cases of menopausal insomnia were divided into two groups: treatment group treated by Gengnian'anshen Decoction and control group treated by estazolam.After one month later,observe the changes of clinical symptoms and signs,sleeping time,sleeping evaluation form and endocrine changes.Result::①The treatment group of menopausal patients with insomnia have a significient change on clinical symptom,and its efficacy compared with the control group were statistically significant;②The total effective rate of the treatment group was 86.7%,and the total effective rate of the control group was 66.7%.The difference between the two groups was statistically significant(P＜0.05),the efficacy of the treatment group was superior to the control group.③The endocrine level:The patients who were treated with estazolam have no significant changes after the treatment.There have no significant changes after the treatment who was treated with Gengnian'anshen Decoction,but the treatment group have a certain effect on regulating the sex hormone levels.④There have no significant adverse reaction and side effects during the treatment.Conclusion::Gengnian'anshen Decoction can improve the sleeping quality,regulate the sex hormone levels,and it can also reduce the clinical symptom such as hot flashes,sweat,anxiety,irritability, dizziness,tinnitus,forgetful,palpitation and so on.From this observation we can sure that the Gengnian'anshen Decoction have an positive effect in treating menopausal insomnia.