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Studies On The Chemical Constituents To Inhibite Aldose Reductase Of Wild-Salvia Miltiorrhiza Bunge

Posted on:2010-11-25Degree:MasterType:Thesis
Country:ChinaCandidate:P F YuFull Text:PDF
GTID:2144360275988277Subject:Medicinal chemistry
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Salvia MiltiorrhizaBunge,a weed of the composite family,is widely distributed in China,and has been used as a traditional Chinese folk medicine for a long time。Studies of the activities show that Salvia Miltiorrhiza Bunge has depressing the blood sugar activity, inhibiting Aldose Reductase activity,anti-inflammatory activity,antimicrobial activity,cardiovascular activity and antileukemia antivity。Among the total,acetic ether and n-butanol extractant is the active position of inhabiting Aldose Reductase.Flavonoids is the capital active component. In this chemical study on Salvia Miltiorrhiza Bunge,after repeating silica gel,we obtained eight compounds,and identified six compounds's structures,The five compounds are: Stigmasterol (Ⅰ),Ursolic Acid(Ⅱ),β-Sitosterol (Ⅲ),Daucosterol (Ⅳ),Baicalin(Ⅳ).
Keywords/Search Tags:Salvia Miltiorrhiza Bunge, Stigmasterol (Ⅰ), Ursolic Acid(Ⅱ), β-Sitosterol (Ⅲ), Daucosterol (Ⅳ), Baicalin(Ⅴ)
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