Objective:To compare the clinical effect of three therapies forⅡ°toⅢ°benign prostatic hyperplasia(BPH),and to discuss the feasibility of the endoscopic technique in the treatment of large volume BPH.Methods:Clinical data of 68 cases of BPH aboveⅡ°treated with surgery in our institute nearly 2 years were investigated retrospectively.Of the 68 patients, 27underwent transurethral electroresection of prostate,20 were subjected to transurethral plasmakinetic resection of prostate,21 suffered suprapubic prostatectomy.In the present study,the occurrence in the operative period and complications such as operation time,volume of blood loss in the operative period, exsiting time of catheter,occurrence of complications after the operation and hospitalization period were analyzed and compared.International prostate symptom score(I-PSS),quality of life score(QoL),maximum flow rate(QMax),Postvoid residual urine(PVR) were assessed in the preoperative period,at the 3rd month after the operation.Results:The results of three therapies were satisfactory.No patients died,all were cured and discharged from hospital.There was no significant difference of the general situation and complications,however,there were statistically significant differences of the age among the three groups.There was a significant difference of operation time and volume of blood loss in the operative period.There was no significant difference of exsiting time of catheter and hospitalization period between TURP and PKRP groups,but transurethral endoscopic resection significantly differed from open surgery(SPP).There was no significant difference of I-PSS,QOL,Qmax, PVR at the 3rd month after the operation among the three groups,however,There were statistically significant differences of I-PSS,QOL,Qmax,PVR in the preoperative period.CONCLUSION:(1) TURP was more suitable for older persons than open surgery(SPP) in the treatment ofⅡ°toⅢ°BPH.(2) Compared with open surgery,transurethral electroresection of prostate and transurethral plasmakinetic resection of prostate had much dominant such as less blood loss,less trauma and quicker recovery,fewer complications.The effect of PKRP was better about volume of blood loss especially in the intraoperative and postoperative period.There is no significant difference of recent efficacy in the treatment.The average period of operation time in the open surgery group were shorter than in TURP and PKRP groups,when therapies for BPH which aboveⅡ°without the TURS complications.(3) With the accumulation of operation experience,the improvement of technology and the development of endoscopic techniques,transurethral endoscopic resection was safe and effective in the treatment ofⅡ°toⅢ°BPH.Endoscopic resection of large volume BPH had a higher security than open surgery,similar in operation time.
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