Effect Of Supplementing Qi To Invigorate The Spleen Herbs On Exercise Endurance In Patients With Stable Chronic Obstructive Pulmonary Disease

Effect of Supplementing Qi to Invigorate the Spleen Herbs on exercise Endurance in Patients with Stable Chronic Obstructive Pulmonary DiseaseObjective To evaluate the effect of supplementing Qi to invigorate the spleen herbs on exercise endurance in patients with stable chronic obstructive pulmonary disease(COPD).Methods 47 patients with stable COPD,37 males and 10 females,with a median age of 71.91±6.91 years,were collected in out-patient of the First Affiliated Hospital of Zhejiang College of TCM from April 2008 to March 2009.They were diagnosed lung distension after syndrome differentiation of TCM,belong to the type of insufficiency of lung-qi and spleen-qi. Their pulmonary function tests were moderate to severe ventilatory dysfunction(30%≤FEV1 of Pred＜80%).Exclusion criterias were serious lung diseases,serious heart disease and limb dysfunction.Patients were randomly divided into the control group(n=23) and the treatment group(n=24).The control group quit smoking and was treated by oral Theophylline Controlled Release Capsule,and the treatment group was treated by supplementing Qi to invigorate spleen herbs,quit smoking and oral Theophylline Controlled Release Capsule for two months.We measured ptients lung function(FEV₁%),body mass index(BMI) and 6MWD.The results were analyzed by statistical package for social science(SPPS version 15.0),measurement data were expressed by(?)±s,t test was used for the comparison of the normal distributional data and Wilcoxon test was used for the comparison of skewed distributional data.Chi-square test was used for the comparison of count data. Results 1.6MWD in the treatment group increased 72 metres(before treatment:402.58±92.33 m,after treatment:474.21±82.57 m,P＜0.01),and that in the control group increased 33 metres(before treatment:363.70±77.11 m,after treatment:396.61±76.86 m,t=7.229,P＜0.01) after treatment.6MWD in the treatment group(474.21±82.57 m)was was higher than that in the control group(396.61±76.86 m) after treatment(P＜0.01).2.FEV₁%of lung function were no statistical significance(P＞0.05) among two groups before and after treatment.3. The weight in he treatment group after treatment(59.81±9.94 Kg) was higher than that of before treatment(59.54±10.16Kg)(P＜0.01).4.The BMI in the treatment group after treatment(22.96±3.34 Kg/m²) was higher than that of before treatment(22.47±3.56 Kg/m²)(t=5.684,P＜0.01).Conclusion 1.Supplementing Qi to invigorate the spleen herbs have the effect to improve the 6MWD in the pateints of stable COPD and the type of insufficiency of lung-qi and spleen-qi, which suggests this method could improve the exercise endurance and activity capacity of patients.2.Supplementing Qi to invigorate the spleen herbs can improve BMI in the pateints. 3.Theophylline Controlled Release Capsules have the effect to improve 6MWD in patients of stable COPD,but cannot improve the patients' weight.4.Supplementing Qi to invigorate the spleen herbs and theophylline Controlled Release Capsules cannot improve FEV₁%of the lung function.Subject words COPD 6MWD Supplementing Qi to invigorate the spleen Herbs...