Clinical Analysis On Correlation Of Ankle-brachial Index, Fibrinogen And Carotid Artery Atherosclerosis In Patients With Cerebral Infarction

ObjectiveTo investigate the correlation of ankle-brachial index (ABI), fibrinogen and carotid artery atherosclerosis in patients with cerebral infarction, and find the risk factors that cause cerebral infarction.MethodsFrom Feb 2009 to Jun 2009 in Ninth People' Hospital of Shenyang,100 in hospitaled patients with cerebral infarction were selected as the test group; and 80 outpatients with no cerebral infarction in the same period were selected as the control group. ABI was examined by ES-1000 SPM Doppler diagnostic instrument. PHILIPS-iU22 colour ultrasonic Doppler examinations were performed in both groups to compare with the conditions of carotid artery atherosclerosis.And in the same time,every patient'risk factors, such as age,gender,blood pressure, free plasma glucose (FPG), total cholesterol (CHO), Triglyceride (TG), high densitylipoprotein-cholesterol (HDL-C), low densitylipoprotein-cholesterol (LDL-C), Fibrinogen (FIB), ABI,the history of smoke and drink were collected,and then analized in statistical methods,to find the differents between the two groups.ResultsThere was no significant difference in HDL-C and CHO between cerebral infarction group and control group(P＞0.05).while there were significant differences in ABI,FIB,LDL-C,TG,FPG between the two groups(P＜0.05),whether the patient had the history of hypertension and smoke,and whether carotid artery atherosclerosis had occured made significant differences between the two groups(P＜0.05). Among the risk factors drink history were not associated with the happening of cerebral infarction(P＞0.05). Among the 100 patients with cerebral infarction,73cases(73.00%) were found arteriosclerosis spots at the segment outside skull of carotid; Arteriosclerosis spots were easily broken out at BIF,then at CCA.And among the 80 outpatients in the control group,23cases(28.75%) were found arteriosclerosis spots. There was significant difference between the two groups(P＜0.01).Logistic regression analysis indicated that ABI,FIB,TG and carotid artery arteriosclerosis spots were independent predictors of cerebral infarction.ConclusionsAmong the risk factors,except of age, higher FIB,LDL-C,TG,FPG and lower ABI were associated with the happening of cerebral infarction. Hypertension,smoke and carotid artery atherosclerosis spots were all the risk factors of cerebral infarction. Among those risk factors, ABI,FIB,TG and carotid artery arteriosclerosis spots were independent predictors of cerebral infarction.